摘要
胰升糖素样肽1（glucagon-like peptide-1, GLP-1）是一种经食物刺激后主要由回肠末端、结肠和直肠中 L 细胞产生和分泌的肠促胰岛素,它可以与体内 GLP-1受体结合,发挥一系列的生物学效应。近年来研究表明,GLP-1通过减少内质网应激,参与了多种疾病的发生及发展。
Glucagon-like peptide-1（GLP-1） is an incretin stimulated by food mainly produced and secreted from L-cells in terminal ileum, colon and rectum. It can be combined with GLP-1 receptors, and then plays a series of biological effects. In recent years, studies have shown that GLP-1 participates in the occurrence and development of many diseases.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2015年第2期188-191,共4页
Chinese Journal of Endocrinology and Metabolism
基金
国家自然科学基金面上项目（81370956）
关键词
胰升糖素样肽
1
内质网应激
Glucagon-like peptide-1
Endoplasmic reticulum stress
