摘要
目的:探讨红细胞分布宽度(RDW)与非瓣膜病心房颤动(房颤)患者发生缺血性脑卒中的关系。方法:入选2012年11月-2013年11月诊断为非瓣膜病房颤的住院患者,患者出院后每3个月随访1次,随访期间患者发生缺血性脑卒中或随访期满1年则随访终止,根据随访结果将患者分为脑卒中组和非脑卒中组。通过Logistic回归分析及ROC曲线分析研究RDW对非瓣膜病房颤患者发生缺血性脑卒中的预测价值。结果:脑卒中组患者的RDW较非脑卒中组患者偏高(P<0.001)。高RDW是非瓣膜病房颤患者发生缺血性脑卒中的独立危险因素(OR=2.465,P<0.001),其预测非瓣膜病房颤患者发生缺血性脑卒中的ROC曲线下面积为0.758(P<0.001)。结论:RDW对非瓣膜病房颤患者发生缺血性脑卒中有预测价值,预测的最佳截断值为13.55。
Objective：To explore the relationship of red blood cell distribution width（RDW）and ischemic stroke in patients with non-valvular atrial fibrillation（NVAF）.Methods：The inpatients who were diagnosed with NVAF were selected during November 2012 to November 2013,the patients were seen for follow-up visits once every three months after that they discharged from hospital,the follow-up visit finished when the patient suffered ischemic stroke during the follow-up period or the patient was followed up for 1year.They were divided into stroke group and non-stroke group according to the follow-up result.It was researched that the predictive value of RDW for the risk of ischemic stroke in patients with NVAF by the Logistic regression analysis and the ROC curves.Results：The RDW of the patient in the stroke group was higher than that in the non-stroke group（P〈0.001）.The high RDW was independent risk factor of ischemic stroke in patients with NVAF（OR=2.465,P〈0.001）.The area under the ROC curve of RDW was 0.758 to predict the happening of ischemic stroke in patients with NVAF（P〈0.001）.Conclusion：The RDW may predict the ischemic stroke in patients with NVAF,and 13.55 is the best cutoff value.
出处
《医学理论与实践》
2015年第6期716-718,共3页
The Journal of Medical Theory and Practice
关键词
红细胞分布宽度
非瓣膜病心房颤动
缺血性脑卒中
Red blood cell distribution width
Non-valvular atrial fibrillation
Ischemic stroke
