摘要
目的:研究朴术颗粒的提取工艺。方法:以厚朴酚与和厚朴酚总含量、得膏率为指标,采用单因素、多因素试验法优选提取工艺。结果:五味药材水提取得膏率较高,水提醇沉和50%醇提有效成分转移率较高;白术、陈皮、厚朴提取工艺,60%、70%、80%乙醇提取效果无明显差异,优于50%乙醇,提取次数为主要影响因素,提取时间、溶剂量为次要因素。结论:白术、陈皮、厚朴最优提取工艺为A3B2C2,即60%乙醇提取3次,加入乙醇量分别为药材量的8倍、6倍、4倍,1.5h/次。
Objective：To investigate the extraction process of Puzhu Granule.Methods：Using the content of Magnolol and Honokiol and extracting ratio as evaluating indexes,we selected the optimum extracting condition by one-way and orthogonal design.Results：The extracting ratio was higher when five medicinal herbs were extracted in water.The metastasis of active ingredients was higher when we used water extraction and alcohol precipitation or 50%alcohol extraction.The extraction effects of 60%,70%,80% alcohol had no significant difference and better than 50% alcohol.Extraction times was the major influence factor,extraction time and solvent volume were the minor factors.Conclusion：The optimum extracting condition was A3B2C2：extracting 3times using 60% alcohol,adding alcohol for 8,6,4times and extracting for 1.5h,respectively.
出处
《医学理论与实践》
2015年第5期561-562,565,共3页
The Journal of Medical Theory and Practice
关键词
朴术颗粒
提取
最优工艺
提取次数
Puzhu Granule
Extraction
Optimum process
Extraction times
