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培美曲塞治疗老年ⅢB~Ⅳ期非小细胞肺癌的效果观察

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摘要 目的观察培美曲塞治疗老年ⅢB~Ⅳ期非小细胞肺癌(NSCLC)的临床疗效及不良反应。方法培美曲塞二钠500mg/m^2,从第1天给药,21d为1个周期,完成2个周期以上化疗后评价疗效和不良反应。结果24例患者,完全缓解(CR)0例,部分缓解(PR)5例,稳定(SD)13例,进展(PD)6例,有效率(RR)为20.8%,临床获益率为75.0%。主要不良反应为骨髓抑制和消化道反应。结论培美曲塞治疗老年ⅢB~Ⅳ期NSCLC疗效较好,不良反应较轻,耐受性较好。
作者 张玲
出处 《常州实用医学》 2015年第1期21-22,共2页 CHANGZHOU PRACTICAL MEDICINE
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