摘要
目的探讨氧合指数与急性呼吸衰竭行有创通气治疗患者预后的关系。方法选取2008年1月至2012年10月山东省即墨市人民医院行有创通气治疗急性呼吸衰竭患者75例,其中死亡28例,设为死亡组,存活47例,设为存活组;比较两组患者行有创通气治疗前急性生理与慢性健康状况(APACHE)Ⅲ评分、多器官功能障碍综合征(MODS)评分,治疗1、3、7 d后氧合指数(Pa O2/Fi O2)、动脉血二氧化碳分压(Pa CO2)及p H值等血气分析指标水平。结果存活组和死亡组患者行有创通气治疗前急性生理学与慢性健康状况评分Ⅲ(APACHEⅢ)评分和多器官功能障碍综合征(MODS)评分组间比较差异无统计学意义(P>0.05);存活组和死亡组患者治疗1 d后Pa O2/Fi O2、Pa CO2及p H水平组间比较差异无统计学意义(P>0.05);两组患者治疗3、7 d后Pa CO2和p H水平组间比较差异无统计学意义(P>0.05);但死亡组患者治疗3、7 d后Pa O2/Fi O2水平明显低于存活组(P<0.05);存活组和死亡组在治疗后不同时间(1、3、7 d)的Pa O2/Fi O2和Pa CO2比较差异有统计学意义(P<0.05)。结论氧合指数与急性呼吸衰竭行有创通气治疗患者预后关系密切,可作为临床评价重要参考指标之一。
Objective To explore the relationship between oxygenation index and prognosis of patients with acute respiratory failure after invasive ventilation therapy. Methods From Shandong Province Jimo City People＇s Hospital from Jan. 2008 to Oct. 2012,75 patients with acute respiratory failure receiving invasive ventilation were included in the study,including 28 cases of death as death group,47 cases of survival assurvival group; the APACHEⅢ score,MODS score of the two groups before invasive ventilation were compared,the blood gas indexes such as oxygenation index（ Pa O2/ Fi O2）,arterial blood carbon dioxide partial pressure（ Pa CO2） and p H value during treatment were compared. Results The APACHEIII score and MODS score of both groups before invasive ventilation had no statistically significant difference（ P 0. 05）; after 1 d treatment the Pa O2/ Fi O2,Pa CO2 and p H level of both groups had no statistically significant difference（ P 0. 05）; after 3 d,7 d treatment the Pa CO2 and p H level of both groups had no statistically significant difference（ P 0. 05）; but the Pa O2/ Fi O2 levels after 3 d,7 d treatment of the death group was significantly lower than the survival group（ P 0. 05）. The Pa O2/ Fi O2 and Pa CO2 of the survival group and death group at different time points（ 1,3,7 d） were not all the same,and the differences were statistically significant（ P 0. 05）. Conclusion The oxygenation index and the prognosis of acute respiratory failure patients after invasive ventilation are closely correlated,thus can be used as an important index for clinical evaluation.
出处
《医学综述》
2015年第2期338-339,共2页
Medical Recapitulate
关键词
急性呼吸衰竭
有创通气
氧合指数
预后
Acute respiratory failure
Invasive ventilation
Oxygenation index
Prognosis
