摘要
目的观察神经节苷脂联合康复治疗老年血管性痴呆的疗效。方法选取2012-01—2013-06我院血管性痴呆患者64例分为2组,对照组31例在降压、降脂、活血等治疗基础上给予康复训练治疗,观察组33例在对照组治疗基础上加用神经节苷脂静脉注射,2组均为2周1个疗程,治疗2个疗程根据MMSE和ADL量表评估临床疗效。结果 2组治疗后MMSE和ADL均显著优于治疗前(P<0.05),且治疗后观察组MMSE和ADL评分显著优于对照组(P<0.05),观察组有效率93.94%显著高于对照组的70.97%,差异均有统计学意义(P<0.05)。结论神经节苷脂联合康复可显著改善血管性痴呆患者的智能障碍程度和日常生活能力,提高患者生活质量。
Objective To observe the clinical curative effect of ganglioside combined with rehabilitation therapy for senilevascular dementia.Methods 64 cases of vascular dementia patients from January of 2012 to June of 2013 were divided into two groups,control group with 31 cases and observation group with 33 cases.The patients of control group were given the treatment of rehabilitation training based on blood pressure,lipid,blood and other foundation treatment.The patients of observation group were given ganglioside intravenous injection,based on the treatment of control group.Two weeks were one course of treatment for both of the two groups.Results Clinical efficacy was evaluated according to MMSE and ADL scales after two courses of treatment.MMSE and ADL of The two groups after treatment were significantly better than those before treatment（P〈0.05）.And after treatment,MMSE and ADL scores of the observation group were significantly better than those of control group（P〈0.05）.The effective rate of observation group was 93.94%,which was significantly higher than that of control group with 70.97%（P〈0.05）.The differences were statistically significance.Conclusion Ganglioside combined with rehabilitation can significantly improve the intelligence impairment and daily living ability of patients with vascular dementia,and improve the quality of life of the patients.
出处
《中国实用神经疾病杂志》
2015年第3期13-15,共3页
Chinese Journal of Practical Nervous Diseases
