摘要
目的探讨康艾注射液联合头孢哌酮/他唑巴坦治疗老年慢性阻塞性肺疾病急性加重期（AECOPD）的临床效果。方法回顾性分析本院2012年1月~2014年1月收治入院的老年AECOPD患者102例,按照治疗方式分为观察组及对照组,各51例,两组均接受常规治疗,对照组采用头孢哌酮/他唑巴坦治疗,观察组在此基础上加用康艾注射液治疗,比较两组治疗后临床症状改善时间,观察两组治疗前后血气分析、肺功能情况。结果观察组治疗后的pH、PaO2、PaCO2、FEV1%预计值、FEV1/FVC与治疗前比较差异有统计学意义（t=1.923、2.038、2.165、2.055、2.476,P〈0.05）;对照组治疗后的PaO2、PaCO2、FEV1%预计值、FEV1/FVC与治疗前比较差异有统计学意义（t=1.896、1.988、2.012、2.186,P〈0.05）;观察组治疗后的pH、PaO2、PaCO2、FEV1%预计值、FEV1/FVC与对照组比较差异均有统计学意义（P〈0.05）。结论康艾注射液联合头孢哌酮/他唑巴坦治疗老年AECOPD的效果良好。
Objective To investigate effect observation of Kangai injection combined with cefoperazone/tazobactam in the treatment of elderly patients with AECOPD. Methods 102 elderly patients with AECOPD in our hospital from January 2012 to January 2014 were retrospectively analyzed and divided into observation group and control group in accordance with the treatment method,each group of 51 cases.Routine treatment was used in two groups,cefoperazone/tazobactam was applied in control group,Kangai injection was used in observation group on the basis of control group.The clinical symptom improved time were compared between two groups after treatment,and before and after treatment in patients with blood gas analysis,pulmonary function in two groups were observed. Results After treatment,p H,Pa O2,Pa CO2,FEV1% pre,FEV1/FVC in observation group was statistical difference compared with before treatment respectively（t=1.923, 2.038,2.165,2.055,2.476,P〈0.05）.After treatment,Pa O2,Pa CO2,FEV1% pre,FEV1/FVC in control group was statistical difference compared with before treatment respectively（t =1.896,1.988,2.012,2.186,P 0.05）.After treatment,p H,Pa O2,Pa CO2,FEV1% pre,FEV1/FVC in observation group was statistical difference compared with control group respectively（P〈0.05）. Conclusion Kangai injection combined with cefoperazone/tazobactam in the treatment of elderly patients with AECOPD has good effect.
出处
《中国当代医药》
2015年第6期129-131,共3页
China Modern Medicine
