摘要
目的:探讨玻璃化冻融胚胎移植妊娠结局的影响因素。方法:对接受玻璃化冻融胚胎移植患者的247个周期进行回顾性分析,根据患者的临床结局分为妊娠组(112例)和非妊娠组(135例)。对年龄、不孕原因、受精方式、冻融胚胎移植次数、移植胚胎数目、胚胎质量、子宫内膜厚度、子宫内膜准备方案、冻胚时间等9个可能影响因素进行分析。结果:妊娠组与非妊娠组的冻胚时间和子宫内膜厚度均有统计学差异(χ2=8.703,P=0.003;χ2=2.838,P=0.009),logistic多因素回归分析结果显示冻胚时间和子宫内膜厚度与妊娠结局有关。结论:玻璃化冻融胚胎移植受精后第3天冻胚比第2天冻胚的胚胎临床妊娠率更高;在一定范围内,移植日子宫内膜厚度>11.0mm比≤11.0mm患者的妊娠率更高。
Objective：To explore the influencing factors of the outcome of the vitrification-thawed embryo transfer.Methods：A retrospective analysis was conducted on the related data of 247 cases who underwent the vitrification-thawed embryo transfer.Patients were divided into pregnancy group（n=112）and non-pregnancy group（n=135）.Nine possible influencing factors including age,cause of infertility,fertilization method,frozen-thawed embryo transfer cycles,embryo number transferred,embryo quality,endometrial thickness,endometrial preparation program,cryopreservation timing were analyzed.Results：The differences of the cryopreservation timing（χ^2=8.703,P=0.003）and the endometrial thickness（χ^2=2.838,P=0.009）between the pregnancy group and the non-pregnancy group were significant.Logistic regression analysis results showed that the cryopreservation timing and the endometrial thickness were related to pregnancy outcome.Conclusion：In vitrification-thawed embryo transfer,the clinical pregnancy rate of D3 embryo is higher than D2 one,and within a certain range,the clinical pregnancy rates of women with more than 11.0 mm of the endometrial thickness are higher than those with not more than 11.0mm of the endometrial thickness.
出处
《中国计划生育学杂志》
2015年第3期178-181,共4页
Chinese Journal of Family Planning
关键词
玻璃化冻融胚胎
影响因素
logisic模型
多因素回归分析
辅助生殖技术
Vitrification-thawed embryo
Influencing factors
Logistic model
Multi-factor regression analysis
Artifi-cial reproductive technology
