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布比卡因复合舒芬太尼、右美托咪定蛛网膜下腔阻滞麻醉在剖宫产术中的应用 被引量:14

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摘要 目的:探讨布比卡因联合舒芬太尼、右美托咪定蛛网膜下腔阻滞麻醉在剖宫产术中的应用。方法:择期行剖宫产手术的患者120例,随机分为三组:布比卡因组(B组):蛛网膜下腔注射0.5%布比卡因10 mg;舒芬太尼+布比卡因组(SB组):蛛网膜下腔注射0.5%布比卡因10 mg+舒芬太尼5μg;右美托咪定+布比卡因组(DB组):蛛网膜下腔注射0.5%布比卡因10 mg+右美托咪定10μg,每组40例。蛛网膜下腔穿刺成功后,将混合液注入蛛网膜下腔,速率0.1 ml/s。记录感觉阻滞、运动阻滞情况、术中疼痛程度、腹肌松弛程度和牵拉反应程度、术中低血压、心动过缓、呼吸抑制、恶心、呕吐、寒颤及瘙痒等不良反应的发生和处理情况及新生儿体重、出生后1 min和5 min Apgar评分。结果:DB组较SB组感觉、运动阻滞起效时间缩短,持续镇痛作用时间延长,腹肌松弛程度高,牵拉反应程度低,瘙痒、寒颤发生率低,差异有统计学意义(P<0.05),三组间低血压、心动过缓、呼吸抑制、恶心、呕吐发生率,麻黄碱、阿托品使用率及新生儿体重、出生后1 min和5 min Apgar评分组间比较差异无统计学意义(P﹥0.05)。结论:剖宫产术重比重布比卡因复合右美托咪定较复合舒芬太尼感觉、运动阻滞起效时间缩短,持续镇痛作用时间延长,腹肌松弛程度高,牵拉反应程度低,瘙痒、寒颤发生率低,值得临床应用。
出处 《吉林医学》 CAS 2015年第7期1350-1353,共4页 Jilin Medical Journal
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参考文献15

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