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2型糖尿病患者合并肾病的临床特点及发病率的影响因素 被引量:12

Analysis of clinical characteristics and morbidity factors for diabetic nephropathy in type 2 diabetes mellitus patients
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摘要 目的:探讨2型糖尿病患者合并肾病临床特点以及发病率的影响因素。方法:对296例2型糖尿病患者进行身体测量、实验室指标检验并统计分析。结果:糖尿病肾病组(DN组)病程比DM组长,DN组有糖尿病家族史患者的比例、合并视网膜病变及高血压的比例、体重指数(BMI)、收缩压、舒张压、血尿素氮(BUN)、尿酸(UA)及肌酐(SCr)均比DM组高,DN组糖化血红蛋白低于DM组,且两组间差异有统计学意义(P<0.05)。BMI<24,SBP<130 mm Hg(1 mm Hg=0.1333 k Pa)是2型糖尿病肾病的保护因素,有糖尿病家族史、DM病程>5年、伴糖尿病视网膜病变、高血压、脑梗死、冠状动脉粥样硬化、SCr高、BUN高、UA高等是影响2型糖尿病肾病发生发展的危险因素。结论:应对糖尿病家庭史以及病程较长的2型糖尿病患者进行定期监测,要以控制血糖、调节血脂、抗高血压、保护肾功能等综合治疗措施防止糖尿病肾病发生、发展。 Objective To investigate the relative factors that affect the renal functions. Methods 296 type 2 diabetic in—patients were investigated by the same questionnaires and laboratory measurements. Results The diabetic family history,diabetic pathogenesis,systolic pres-sure,diastolic pressure,BMI,SCr,BUN and UA of the case group were higher than the control group( P〈0. 05). The HbA1C of the case group were lower than the control group( P〈0. 05). The morbidity rates of both retinopathy and hypertension in case group were higher than the type2 diabetes group(P〈0. 05). Conclusion In one hand,undertaje body test timely,control blood pressure,blood sugar,blood lipids rig-idly,on the other hand,strengthen the health education,promote scientific lifestyle to improve the prevention and control of diabetic nephropa-thy.
出处 《吉林医学》 CAS 2015年第6期1123-1125,共3页 Jilin Medical Journal
关键词 2型糖尿病 糖尿病肾病 影响因素 Type 2 diabetes Diabetes nephropathy Morbidity factor
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