摘要
目的:探讨《内经》病机十九条中"诸寒收引皆属于肾"对类风湿性关节炎(RA)中医治疗的指导作用。方法:主要从发病机制、临床表现和治则治法等角度进行集中阐述。结果:总结从"温阳"、"补肾"立法治疗RA的古今医家用药思路,遣方用药各有特色,但总宗"温阳""补肾"之法,切中RA肾虚为本,邪实为标的病机,肾虚是类风湿性关节炎发病的内在因素,风寒湿邪是其外因。结论:温阳补肾类中药有促进骨髓基质细胞增殖分化和调节免疫功能的作用,提示其改善RA免疫失调和骨质破坏等症状的潜力,为RA临床治疗提供了新的思路,然而,目前中药治疗类风湿性关节炎尚缺乏高质量的临床试验,使得研究结论的可靠性有待进一步证实。
Objective： To explore the guidance of contraction due to internal cold indicates kidney disorders from nineteen pathomechanisms in Huangdi＇s Internal Medicine in TCM（ traditional Chinese medicine） treatment of RA（ rheumatoid arthritis）. Method： In this article,we elaborated our opinion from the perspective of pathogenesis,clinical manifestation and therapeutic principle and method. Results： In the treatment of RA using warming Yang and tonifying kidney method,ancient and modern physicians had their own features,but all complied to the therapeutic principle of warming yang and tonifying kidney and cut into the pathogenesis of deficiency in nature and excess in superficiality,as kidney deficiency is the intrinsic factor and cold origin is the external cause for the onset of rheumatoid arthritis. Conclusion： Chinese herb with the function of warming yang and tonifying kidney can promote differentiation and proliferation of bone marrow stromal cells and adjust the immune function,and thus may be used in improving the RA immune disorders,bone destruction and other symptoms. However,we still lack of high quality clinical trials of TCM treatment in RA,which makes the reliability of the research conclusion remains to be further confirmed.
出处
《中华中医药学刊》
CAS
北大核心
2015年第3期599-603,共5页
Chinese Archives of Traditional Chinese Medicine
基金
国家"十二五"科技支撑计划项目(2013BAI102B10)
北京中医药大学创新团队项目(2011-CXTD-03)
关键词
类风湿关节炎
病机十九条
肾虚为本
寒主收引
温阳补肾
rheumatoid arthritis
nineteen items of pathogenesis
kidney deficiency
cold inducing contraction
warming Yang and tonifying kidney
