摘要
目的应用Spectralis频域OCT（spectral—domain optical coherence tomography，SD—OCT）测量正常人黄斑区视网膜厚度及容积。方法临床实验研究。对2009年6月至2013年9月在河北医科大学第二医院眼科采用Spectralis SD-OCT，对72名正常人136只眼，以直径1、3、6mm ETDRS对黄斑区进行分区，分析黄斑区视网膜厚度、容积隋况。结果黄斑中心小凹的厚度为（215．68±15．73）μm，分区中内环上方、鼻侧最厚，下方次之，颞侧最薄；外环上方最厚，鼻侧次之，颞侧、下方最薄；黄斑区内环各分区视网膜容积的变化与厚度变化相一致。经中央区的黄斑横切及纵切视网膜厚度地形图均为双峰“M”形，正常人黄斑区视网膜厚度地形图为开口向颞下的“马蹄形”，各分区视网膜厚度与年龄无明显相关，差异无统计学意义（r=-0．228～0．009，P〉0．05）。结论正常人黄斑区视网膜厚度地形图为开口向颞下的“马蹄形”，经中央区的黄斑横切及纵切视网膜厚度地形图均为双峰“M”形，Speetralis SD-OCT可以准确测量黄斑区视网膜厚度及容积，为临床黄斑区疾病的诊断、治疗及随访提供可靠依据。
Objective To evaluate the macular thickness and cubic volume in nnrmal eyes with spectral-domain optical coherence tomography （SD-OCT） from Spectralis. Methods Macular thick- ness and cubic volume from 136 eyes of 72 normal subjects were measured and analyzed with Ear- ly Treatment Diabetic Retinopathy Study （ETDRS） subfields, which were embedded in Spectralis with diameter of lmm, 3mm and 6mm. Results The thickness of macular, foveola was measured to be 215.68±15.73μm. The retinal thickness of inner superior subfield （ISM） and inner nasal subfield （INM） was thickest; that of inner inferior subfield （IIM） was next to ISM and INM, and that of in- ner temporal subfield was thinnest. Of the outer subfields, the retinal thickness of outer superior sub- field （OSM） was the thickest one; that of outer nasal subfield （ONM） was next to OSM, and that of outer temporal subfield （OTM） and outer inferior subfield （OIM） was thinnest. The changes of cu- bic volume of macula subfields agreed with thickness changes. The transverse section and longitudi- nal section of macula through central area were double-peak and M-shape. Tomography of macular thickness in normal eyes was horse-shoe shape with opening to inferior temporal. No age-related dif- ference was observed in the thickness and cubic volume of macular subfields. Conclusions The to- mography of normal macula is horse-shoe shape with opening toward inferior temporal. Both trans- verse and longitudinal sections of macula through central sector are double-peak and M-shape. SD-OCT can precisely measure macular thickness and cubic volume, providing evidence for the diag-nosis, therapy and follow-up of macular abnormalities.
出处
《中国实用眼科杂志》
2015年第2期142-145,共4页
Chinese Journal of Practical Ophthalmology
基金
2013年河北省省级重大医学科研课题
关键词
光学相干断层扫描
黄斑
视网膜厚度
视网膜容积
Optical coherence tomography
Macula
Retinal thickness
Retinal cubic volume
