摘要
目的分析新辅助化疗治疗穿孔型胃癌的效果。方法选取2010年1月～2012年12月广东省高州市人民医院收治的88例穿孔型胃癌患者，将其平均分成对照组和观察组2组，对照组采用D2根治术治疗，观察组采用新辅助化疗治疗后再行D2根治术治疗，比较分析2组患者的临床疗效。结果观察组患者进行2～4个疗程的辅助化疗治疗以后，根据CT显示，观察组治疗总有效率为63．6％，对照组总有效率为318％，2组经统计学分析，差异具有统计学意义（P〈0.05）。但是在随访的过程中，2组患者的生存率比较，差异无统计学意义。结论穿孔型胃癌患者采用新辅助化疗治疗后行D2根治术治疗短期内可改善患者临床症状，但长期效果和D2胃癌根治术相差无几。
Objective To analyze the effect of neoadjuvant chemotherapy in the treatment of perforated gastric cancer. Methods 88 cases of perforating gastric cancer in the hospital from January 2010 to December 2012 were chosen, the patients were divided into the observation group and the control group, control group received by D 2 radical mastectomy, observation group was treated with neoadjuvant chemotherapy after radical surgery for D 2, the clinical efficacy of two groups were compared. Results The patients in the observation group into （2-4） combined with chemotherapy in the treatment of treatment.According to CT evaluation,the total effective rate of observation group was 63.6%,while that of control group was 31.8%.There was ＇significant difference between two groups （P〈0.05）. But in the process of follow-up, survival rate of two groups were compared, the difference was no significant. Conclusion Perforating gastric cancer treated with neoadjuvant chemotherapy in the treatment of D 2 after radical mastectomy could improve Clinical symptoms,but there was not much difference between D 2 and neoadjuvant chemotherapy after radical surgery for D 2.
出处
《当代医学》
2014年第22期64-65,共2页
Contemporary Medicine
关键词
新辅助化疗治疗
胃癌
穿孔
D2根治术
Neoadjuvant chemotherapy
Gastric cancer
Perforation
D 2 radical operation
