期刊文献+

系统性红斑狼疮的免疫学检验联合检测诊断价值研究 被引量:6

下载PDF
导出
摘要 目的研究IgA、IgM、IgG、C3、C4、可提取核抗原(ENA)、抗核抗体(ANAS)、抗双链脱氧核糖抗体(ds-DNA)几种免疫学抗体联合检测诊断系统性红斑狼疮的价值。方法对活动期系统性红斑狼疮、非活动期系统性红斑狼疮及健康者进行免疫学联合检测,并对比分析检测结果。结果系统性红斑狼疮活动组的IgA、IgM、IgG水平均明显高于健康者,差异有统计学意义(P<0.01),C3、C4指标明显低于健康者,差异有统计学意义(P<0.01);系统性红斑狼疮非活动组的IgA、IgG水平均高于健康者,差异有统计学意义(P<0.05),其余指标与健康者差异无统计学意义(P>0.05)。结论免疫学检验联合检测对于诊断系统性红斑狼疮具有临床参考价值,可用于判断系统性红斑狼疮的病情进展。
出处 《中国实用医药》 2014年第20期70-71,共2页 China Practical Medicine
  • 相关文献

参考文献3

二级参考文献22

  • 1Hagiwara E,Gourley M, Lee S, et al. Disease severity in patients with systemic lupus erythematosus correlates with an increased ratio of IL-10: IFN-γ-secreting cell in the peripheral blood [J].Arthritis Rheum,1996,39(3):379-385. 被引量:1
  • 2Llorente L, Zou W, Levy Y, et al. Role of interleukin-10in the B lymphocytes hyperactivity and autoantibody production of human SLE[J]. J Exp Med,1995,181(3):839-844. 被引量:1
  • 3Merke PA.Chang Y.Pierangeli SS.et al.The prevalence and clinical associations of anticardiolipin antibodies in a large inception cohort of patients with connective tissue diseases[J].Am J Med,1996.101(1):579-583. 被引量:1
  • 4Schorer AE.Nicholus WR.Kathleen V.et al.Lupus anticougulant indrces a selective defect in thrombin-mediated endothelid prostacyclin releases and platelet aggregation[J].Br J Haemcotol,1989.71(3):399-407. 被引量:1
  • 5Le Kowith JB.Gilkeson GB.Nephritogenic autoantibodies inlupus[J].Arthritis Rheum,1996.39(6):894-903. 被引量:1
  • 6Tan E M,Von-Muhlen C A.Autoantibodies in the diagnosis of systemic rheumatic disease[J].Semin Arthritis Rheum,1995,24(5):323. 被引量:1
  • 7Cairns G,McMillan S A,Crockard A D,et al.Antinucleosome antibodies in the diagnosis of systemic lupus erythematosus[J].Ann Rheum Dis,2003,62:272-273. 被引量:1
  • 8Servais G,Daens S,Guillaume M P,et al.Diagnostic specificities and sensitivities of anti-ds-DNA,anti-membrane DNA and anti-nucleosomes autoantibodies[J].Scand J Clin Lab Invest Suppl,2001,235:61-67., 被引量:1
  • 9Hochberg M C.Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus[J].Arthritis Rheum,1997,40:1725. 被引量:1
  • 10Thomas C,Robinson J A.The antinuclear antibody test.when is positive result clinically relevant?[J].Postgrad Med.1993,94:55-58. 被引量:1

共引文献9

同被引文献39

引证文献6

二级引证文献39

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部