摘要
目的探讨红细胞分布宽度(RDW)与缺血性脑卒中患者近期预后的关系。方法选取2012年5月—2014年5月武钢大冶铁矿职工医院收治的92例缺血性脑卒中住院患者作为卒中组,并将缺血性脑卒中患者分为A组(n=79,为90 d内未再发脑梗死住院或死亡患者)和B组(n=13,为90 d内再发脑梗死住院或死亡患者);另选取同期在武钢大冶铁矿职工医院门诊进行体检的73例体检健康者作为对照组。收集研究对象的一般资料、入院后24 h内血常规、生化全套指标,并采用多因素Logistic回归分析缺血性脑卒中患者近期预后不良的危险因素。结果卒中组患者年龄、体质指数、高血压和糖尿病发生率、白细胞计数(WBC)、RDW、尿素氮、空腹血糖、总胆固醇(TC)、三酰甘油(TG)及超敏C反应蛋白(hs-CRP)均高于对照组,A组患者年龄、高血压和糖尿病发生率、WBC、RDW、空腹血糖及hs-CRP低于B组(P<0.05);多因素Logistic回归分析结果显示,年龄、高血压、WBC、RDW及hs-CRP是缺血性脑卒中患者近期预后不良的独立危险因素。结论缺血性脑卒中患者RDW明显升高,且RDW是患者近期预后不良的独立危险因素之一。
Objective To investigate the relationship between red blood cell distribution width( RDW) and short-term prognosis of ischemic stroke patients. Methods From May 2012 to May 2014,92 ischemic stroke patients were selected as case group in the Work's Hospital of Daye Iron Mines of Wuhan Iron and Xteel Group,and they were divided into subgroups A (without recurrence of cerebral infarction or death)and B(with recurrence of cerebral infarction or death),according to the prognosis within 90 days;a total of 73 healthy cases were selected as control group at the same time. General information,blood routine examination and whole biochemistry index within 24 hours after admission were retrospectively analyzed,and risk factors of short - term poor prognosis were analyzed by multiple Logistic regression analysis. Results Age, BMI, incidence of hypertension and diabetes,WBC,RDW,blood urea nitrogen,fasting blood glucose,TC,TG and hs -CRP of case group were higher than those of control group(P﹤0. 05);age,incidence of hypertension and diabetes,WBC,RDW,fasting blood glucose and hs-CRP of A group were lower than those of B group ( P ﹤0. 05 );multiple Logistic regression analysis showed that,age,hypertension,WBC,RDW and hs-CRP were risk factors of short-term poor prognosis of ischemic stroke patients (P﹤0. 05). Conclusion RDW of ischemic stroke patients is higher,and it is an independent risk factor of short-term poor prognosis.
出处
《实用心脑肺血管病杂志》
2015年第1期23-26,共4页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
脑缺血
红细胞分布宽度
预后
Brain ischemia
Red blood cell distribution width
Prognosis
