摘要
目的了解我校教职工血清尿酸（UA）水平及高尿酸血症的分布特点,为进行高尿酸血症的防治工作提供一定科学依据。方法用尿酸酶法测定4 893例健康体检者血清UA,男性UA〉428μmol/L女性UA〉357μmol/L为高尿酸血症判断标准。按年龄段进行分组统计。结果该校教职工健康体检人群男性血清UA平均水平（357.23±75.17）μmol/L明显高于女性（269.44±65.34）μmol/L,差异有统计学意义（P〈0.05）。男性20-〈30,30-〈40岁人群血清UA水平和高尿酸血症患病率最高,60-〈70年龄人群的最低,差异有统计学意义（P〈0.05）,20-〈70人群随年龄增加逐渐降低,70-〈80,≥80岁人群相对60-〈70岁人群维持在较高水平,差异有统计学意义（P〈0.05）。女性血清UA水平和高尿酸血症患病率随年龄增加而增高。结论该校教职工男性血清UA水平明显高于女性,而且男性人群中高尿酸血症患者出现年轻化趋势。
Objective To investigate the concentration of blood uric acid and the prevalence of hyperuricemia in staff of a university so as to provide scientific basis for prevention and treatment of hyperuricemia. Methods Uric acid（UA） of 4 893 persons were detected by enzymatic method. For male whose UA〉428 μmol/L,For female whose UA〉357μmol/L were considered as hyperuricemia. People enrolled in the study were grouped according to age and analyzed. Results The average UA of males was （357.23± 75.17） μmol/L and was significantly higher than that of females（P〈0.05）. The average UA concentration and hyperuricemia ratios in males of 20-〈30,30-〈40 years old groups were the highest,that of 60-〈70 group was the lowest,the difference was statistically significant（P〈0.05）. The average UA and hyperuricemia ratios of the male group decreased with age before 70 year old. But The average UA and hyperuricemia ratios of 70-〈80 and ≥80 groups were higher than that of the 60-〈70 group, the difference was statistically significant（P〈0.05）. The average UA and of hyperuricemia ratio of the female group increased with age. Conclusion The average UA concentration of males was significantly higher than that of female,in addition to that,hyperuricemia patients become younger and younger in male population.
出处
《国际检验医学杂志》
CAS
2015年第4期487-488,491,共3页
International Journal of Laboratory Medicine
关键词
尿酸
高尿酸血症
健康体检
uric acid
hyperuricemia
physical examination
