摘要
目的探讨利用64排螺旋CT灌注成像技术对不同分期肾细胞癌进行诊断的临床价值及方法。方法回顾性分析莱芜市人民医院2011年1月至2013年10月收治的41例肾细胞癌患者的临床资料,以病理学检查结果作为临床分期的金标准,比较不同分期肾细胞癌的CT灌注成像经灌注软件包处理后的血流量(Perfusion),血容量(BV),峰值强化(PEI),达峰时间(TTP),平均通过时间(MTT),表面通透性(PS)指标的差异,同时计算CT诊断肾细胞癌分期的诊断学评价指标。结果早期肾细胞癌和晚期肾细胞癌的Perfusion、BV、PEI、MTT、PS参数比较,差异有统计学意义(P<0.05),而TTP参数比较差异无统计学意义(P>0.05)。采用CT灌注成像技术诊断肾细胞癌分期的灵敏度为86.36%、特异度为89.47%、误诊率为10.53%,漏诊率为13.64%,诊断指数为1.758、Youden指数为0.758。结论采用64排螺旋CT灌注成像技术对不同分期肾细胞癌进行诊断具有较高的准确性,值得临床推广使用。
Objective To evaluate the clinical value 64 slice spiral CT perfusion imaging in diagnosis for different stages of renal cell carcinoma.Methods The clinical data of 41 patients with renal cell carcinoma from January2011 to October 2013 were analyzed retrospectively.Using the pathological examination results as gold standard,blood flow perfusion after treatment,blood volume（BV）,peak enhancement（PEI）,time to peak（TTP）,mean transit time（MTT）and permeability surface（PS）were compared in differen stages,evaluation index of CT in diagnosis for renal cell carcinoma staging were calculated.Results There were significant difference on perfusion,BV,PEI,MTT,PS parameters between early and advanced renal cell carcinoma（P〈0.05）,but no significant difference was found on TTP parameters（P〉0.05）.The sensitivity,specificity,misdiagnosis rate,missed diagnosis rate and Youden index of renal CT perfusion imaging were 86.36%,89.47%,10.53%,13.64%,1.758 and 0.758 respetively.ConclusionThere is high accuracy of 64 slice spiral CT perfusion imaging in diagnosis for different stages of renal cell carcinoma,which is worthy of application and promotion.
出处
《检验医学与临床》
CAS
2015年第4期500-501,504,共3页
Laboratory Medicine and Clinic
关键词
64排螺旋CT
不同分期
肾细胞癌
64slice spiral CT
different stage
renal cell carcinoma
