摘要
目的:比较针刺结合中药平肝健脾方与西药氟哌啶醇片治疗小儿抽动症的临床疗效差异。方法:将47例患儿随机分为观察组(25例)和对照组(22例)。观察组采用针刺太冲、百会、中脘、足三里等穴,留针30min,每日1次,针刺10次后休息5天,结合中药平肝健脾方;对照组口服氟哌啶醇片,从小剂量0.05mg/(kg·d)开始,每天2次,两组均30天为一疗程,共治疗3个疗程。采用美国耶鲁抽动症整体严重程度量表,分别于治疗前、治疗30、60、90天后观察两组患儿抽动次数、抽动频率与抽动强度评分,并比较两组疗效及不良反应情况。结果:治疗30、60、90天后观察组总有效率分别为40.0%(10/25)、64.0%(16/25)、76.0%(19/25),对照组分别为59.1%(13/22)、68.2%(15/22)、77.3%(17/22),在治疗30天后对照组疗效优于观察组(P<0.05),在其他时间点两组疗效差异无统计学意义(均P>0.05);两组治疗后各时间点抽动次数、抽动频率、抽动强度评分均较治疗前明显降低(均P<0.05),在治疗30天后对照组各项评分均较观察组降低更明显(均P<0.05),在其他时间点两组比较差异无统计学意义(均P>0.05)。观察组较对照组不良反应出现几率小且程度较轻。结论:针药结合治疗小儿抽动症与西药氟哌啶醇片作用相当,且不良反应小。
Objective To compare the difference in the clinical efficacy on infantile Tourette syndrome between the integrated therapy of acupuncture and pingganjianpi decoction and haloperidol tablets. Methods Forty-seven children were randomized into an observation group （25 cases） and a control group （22 cases）. In the observation group, acupuncture was applied to Taiehong （LR 3）, Baihui （（iV 20）, Zhongwan （CV 12）, Zusanli （ST 36）, etc. The needles were retained for 30 rain. Acupuncture was given once a day and there were 5 days at intervals after 10 times of acupuncture. Additionally, ping gan jianpi decoction was prescribed. In the control group, haloperidol tablets were prescribed, starting from the small dose, 0.05 mg/kg per day, twice a day. The treatment of 30 days made one session and 3 sessions were required. Yale global tic severity scale （YGTSS） was adopted to ohserve tie time, tic frequency and tic severity score before treatment and in 30 days, 60 days and 90 days after treatment in the two groups. The efficacy and adverse reactions were compared between the two groups. Results The total effective rates were 40.0% （10/25）, 64.0% （16/25） and 76.0% （19/25） in the observation group and were 59.1% （13/22）, 68.2% （15/22） and 77.3% （17/22） in the control group in 30 days, 60 days and 90 days after treatment respectively. The effect in 30 days after treatment in the control group was better than that in the observation group （P〈0.05）. The differences at the other time points were not significant between the two groups （all P〉0.05）. The tic time, tic frequency and tic severity score at the each time point after treatment were reducedob viously as compared with those before treatment （all P〈0.05）. Each item score in the control group was reduced obviously as compared with that in the observation group in 30 days after treatment （all P〈0.05）. The differences at the other time points were not significant between the two groups （all P〉0.05�
出处
《中国针灸》
CAS
CSCD
北大核心
2015年第2期141-144,共4页
Chinese Acupuncture & Moxibustion
基金
上海市自然科学基金项目:10ZR1428800
关键词
抽动秽语综合征
针刺疗法
中药
Tourette syndrome
acupuncture therapy
Chinese medicine
