摘要
目的探讨比索洛尔联合稳心颗粒对老年冠心病室性早搏患者QT间期离散度的影响。方法选择2013年7月-2014年1月本院内科诊治的86例冠心病室性早搏患者,随机分为两组,每组各43例,观察组患者接受稳心颗粒合比索洛尔治疗,对照组患者仅接受稳心颗粒治疗。观察并比较两组患者治疗效果,治疗前、后QT间期和室性早搏变化情况。结果治疗4周后,两组总有效率分别为93.0%和74.4%,观察组治疗后总有效率显著高于对照组（P〈0.05）;两组QTd、QTcd和室性早搏均显著降低（P〈0.01）,且观察组均显著低于对照组（P〈0.05）。结论比索洛尔联合稳心颗粒能够显著降低老年冠心病患者室性早搏发生,缩小心肌复极化的离散程度,值得临床推广。
Objective To investigate the effect of bisoprolol combined with metacenter particle on QT dispersion in elderly patients with coronary heart disease and ventricualar premature beat. Methods All 86 cases of patients with coronary heart disease and ventricualar premature beat from July 2013 to January 2014 were selected and randomly divided into two groups, which observation group（43 cases） was treated with metacenter particle and bisoprolol, and control groups was only treated with metacenter particle. The clinical effect, QT dispersion and ventricualar premature beat before and after treatment were compared. Results After 4 weeks treatment, the total efficiency of two groups were 93.0% and 74.4% respectively, and the total efficiency in observation group was higher than that in control group（P〈0.05）; The QTd, QTcd and ventricualar premature beat were both decreased obviously between the two groups（P〈0.01）,and of which in observation group were lower than that in control group（P〈0.05）. Conclusion Bisoprolol combined with metacenter particle can significantly decrease the time of ventricualar premature beat, and decrease the QT dispersion changes in patients with coronary heart disease, and deserve to clinical.
出处
《中国现代医生》
2015年第6期94-96,共3页
China Modern Doctor
关键词
冠状动脉疾病
室性早搏
老年人
比索洛尔
稳心颗粒
QT离散度
Coronary heart disease
Ventricualar premature beat
Elderly
Bisoprolol
Metacenter particle
QT dispersion
