摘要
目的探讨经尿道前列腺切除术（transurethral resection of prostate,TURP）治疗重度良性前列腺增生（benign prostatic hyperplasia,BPH）的有效性和安全性。方法选择本院2008年1月—2013年6月收治的BPH患者120例,其中前列腺体积80-120 ml的重症增生患者48例为观察组,前列腺体积〈80 ml的轻中度患者72例为对照组,两组均行TURP治疗。术后随访6个月,观察两组患者国际前列腺症状评分（international prostate symptom score,IPSS）、刺激症状评分、梗阻症状评分,记录两组手术时间、术中出血量、术后膀胱冲洗时间、留置导尿管时间、住院时间等。计量资料采用t检验,计数资料采用χ2检验,P〈0.05为差异有统计学意义。结果对照组术前IPSS、刺激症状评分、梗阻症状评分分别为（23.7±6.5）、（9.8±4.0）、（13.9±2.5）分,术后分别为（6.8±3.2）、（4.5±1.8）、（2.3±1.1）分;观察组术前分别为（24.6±6.7）（10.3±3.5、（14.3±3.2）分,术后分别为（7.2±3.4）、（4.2±2.1）、（3.1±1.2）分,两组患者手术前后各项评分比较差异均有统计学意义（均P〈0.05）。对照组手术时间、术中出血量、切除前列腺重量分别为（53.4±12.8）min、（285±48）ml、（51.4±11.5）g,观察组分别为（24.6±6.7）min、（460±50）ml、（72.8±14.2）g,两组比较差异均有统计学意义（均P〈0.05）。术后膀胱冲洗时间、留置导尿管时间、住院时间及尿道狭窄、尿失禁、泌尿系感染等并发症发生率差异均无统计学意义（均P〉0.05）。结论 TURP治疗大体积重度BPH的效果和安全性与轻中度相仿,有效性和安全性较好,值得应用。
Objective To investigate the efficacy and safety evaluation of transurethral resection of prostate（TURP） in treatment of severe benign prostatic hyperplasia（BPH）.Methods 120 cases of patients with BPH in our hospital from January 2008 to June2013 were selected,including 48 patients with prostate volume 80- 120 ml（observation group）,72 cases with prostate volume 80ml（control group）,both groups were given TURP treatment.Patients were followed up for 6 months,the international prostate symptom score（IPSS）,irritation symptom score,obstructive symptom score of two groups were observed,and operative time,blood loss,postoperative bladder irrigation time,catheterization time,hospital stay of two groups were recorded and compared.Count data was processed by t- test,measurement data by chi- square test,P0.05 was considered statistically significant.Results Before treatment,IPSS,irritation symptom score,obstructive symptom scores of observation group were（23.7±6.5）,（9.8±4.0） and（13.9±2.5）;IPSS,irritation symptom score,obstructive symptom scores of after treatment were（6.8±3.2）,（4.5±1.8） and（2.3±1.1）.The scores of control group before treatment were（24.6±6.7）,（10.3±3.5） and（14.3±3.2）.The scores of control group after treatment were（7.2±3.4）,（4.2±2.1） and（3.1±1.2）.The scores of the two group after treatment was significantly lower than those before treatment,differences were statistically significant（all P0.05）.The operative time,blood loss,prostate volume of observation group were（53.4 ±12.8）min,（285±48）ml and（51.4±11.5）g,control group were（24.6±6.7）min,（460±50）ml,（72.8±14.2）g.There were significantly differences between the two groups（all P0.05）,postoperative bladder irrigation time,catheterization time,hospital stay and occurrence of postoperative urethral stricture,urinary incontinence,urinary tract infection of two groups were not significantly different（all P0.05）.Conclusion The efficacy of TURP in t
出处
《社区医学杂志》
2015年第1期46-48,共3页
Journal Of Community Medicine
关键词
经尿道前列腺切除术
重度良性前列腺增生
国际前列腺症状评分
Transurethral resection of prostate Severe benign prostatic hyperplasia International prostate symptom score
