摘要
目的：分析塞克硝唑在厌氧菌感染的慢性化脓性中耳炎治疗中的效果，探讨塞克硝唑治疗厌氧菌感染中耳炎的价值。方法选择我院于2012年9月份～2014年8月份收治的197例厌氧菌感染的慢性化脓性中耳炎患者为观察对象，随机分为观察组99例和对照组98例，观察组采用塞克硝唑治疗，对照组采用甲硝唑治疗，跟踪随访，对比两组患者的疗效及病原菌清除率。结果观察组治疗总有效率为97.98%，干耳时间为（5.28±1.19）d，厌氧菌清除率为88.37%，与对照组比较，P＜0.05，具有统计学差异。结论塞克硝唑具有强效抗厌氧菌感染的作用，能够治疗厌氧菌感染导致的慢性化脓性中耳炎。
Objective To analyze the effect of secnidazole for the treatment of chronic suppurative otitis media caused by anaerobic infections. Methods 197 patients with chronic suppurative otitis media caused by anaerobic infections were selected as the objects from September 2012 to August 2014 in our hospitol. They were randomly divided into observation group （n=99） and control group （n=98）. The observation group was treated with secnidazole and the control group was treated with metronidazole. The patients were followed up. The curative effects and pathogen clearance were compared in both groups. Results In observation group, the total effective rate was 97.98%, the dry ear time was （5.28±1.19） d, anaerobic bacteria clearance rate was 88.37%, when compared with the control group, P〈0.05, there was statistical signiifcance. Conclusion The secnidazole had strong activity against anaerobic bacteria infection. It can treat chronic suppurative otitis media caused by anaerobic infections signiifcantly.
出处
《中国继续医学教育》
2015年第4期228-228,共1页
China Continuing Medical Education
关键词
塞克硝唑
厌氧菌感染
慢性化脓性中耳炎
Secnidazole
Anaerobic bacterial infection
Chronic suppurative otitis media
