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microRNAs调控移植的骨骼肌成肌细胞可改善心肌梗死后心功能

The microRNAs regulating transplantation skeletal myoblasts may improve heart function after myocardial infarction
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摘要 microRNAs是一类内源性、非编码的小RNA,具有负性调节基因表达的生物学功能。最近研究发现,人为控制一些microRNAs的表达,通过多种机制可调节骨骼肌成肌细胞可改善心功能,从而可能成为治疗心肌梗死领域的突破口。 The microRNAs is a kind of endogenous and non-coding small RNA ,which possesses biological function negatively regulating gene expression.Recent researches also found that artificial controlling some microRNAs ex-pressions can improve heart function via regulating skeletal myoblasts through multiple mechanisms,so may become a new breakthrough point in myocardial infarction treatment area.
出处 《心血管康复医学杂志》 CAS 2015年第1期91-94,共4页 Chinese Journal of Cardiovascular Rehabilitation Medicine
基金 国家自然科学基金委员会青年科学基金项目(81100069)~~
关键词 微RNAS 心肌梗死 成肌细胞 骨骼肌 MicroRNAs Myocardial Infarction Myoblasts, skeletal
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