抑制白细胞介素-17活性短肽疫苗对ApoE-/-小鼠免疫功能的影响
摘要
白细胞介素17（IL-17）是近年来发现的又一新的细胞因子[1],它主要由活化的T淋巴细胞产生,能诱导多种基质细胞产生多种前炎性细胞因子和造血活性因子,如白细胞介素-6（IL-6）,白细胞介素-8（IL-8）,粒细胞集落刺激因子（GCSF）,肿瘤坏死因子？α（TNF？α）、白细胞介素-1（IL-1）,前列腺素E2（PGE2）等[2-3]。
出处
《实用临床医药杂志》
CAS
2015年第3期126-127,142,共3页
Journal of Clinical Medicine in Practice
参考文献15
-
1Rouvier E,Luciani M F,Mattei M G,et al.CTLA-8,cloned f rom an act ivated T Cell,bearing AU-Rich messenger RNA instability sequences,and homlogous to a Herpesvirus Saimirigene[J].J Immunol,1993,150:5445. 被引量：1
-
2Fossiez f,Djossou O,Chomarat p,et al.T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines[J].J Exp Med,1996,183(6):2593. 被引量：1
-
3Spriggs M K.Int erleukin-17 and its recepter[J].J Clin Immunol,1997,17(5):366. 被引量：1
-
4Nakae,S,Nambu,A,Sudo,K&Iwakura,Y.Suppression of immune induction ofcollagen-induced arthritis in IL-17-deficient mice[J].J Immunol,2003,171:6173. 被引量：1
-
5Bush K A,Farmer K M,Walker J S.Reduction of joint inflammation and bone erosion in rat adjuvant arthritis by treatment with interleukin-17 receptor Ig G1 Fc fusion protein[J].Arthritis Rheum,2002,46:802. 被引量：1
-
6Hurst S D,Muchamuel T,Gorman D M,et al.New IL-17family members promote Th1 or Th2 responses in the lung:in vivo function of the novel cytokine IL-25[J].J Immunol,2002,169:443. 被引量：1
-
7Schwarzenberger P,Huang W,Ye P,et al.Requirement of endogenous stem cell factor and granulocyte-colony-stimulating factor for IL-17-mediated granulopoiesis[J].J Immunol,2000,164:4783. 被引量：1
-
8Schwarzenberger P,La Russa V,Miller A,et al.IL-17 stimulates granulopoiesis in mice:use of an alternate,novel gene therapy-derived method for in vivo evaluation of cytokines[J].J Immunol,1998,161:6383. 被引量：1
-
9Tan W,Huang W,Zhong Q.IL-17 receptor knockout mice have enhanced myelotoxicity and impaired hemopoietic recovery following gamma irradiation[J].J Immunol,2006,176:6186. 被引量：1
-
10Cheng X,Yu X,Ding Y J,et al.The Th17/Treg imbalance in patients with acute coronary syndrome[J].Clin Immunol,2008,127:89. 被引量：1
二级参考文献45
-
1Molet S, Hamid Q. Davoine F, et al. IL-17 is increased in asthmatic airways and induces human bronchial fibroblast to produce cytokines [ J ]. J Allergy Clin Immunol, 2001,108 ( 3 ) :430-438. 被引量：1
-
2Shin HC, Benbernou N, Esrault S, et al. Expression of IL-17 in human memory CD45RO +T lymphocytes and its regulation by protein kinase A pathway[ J]. Cytokine , 1999,11 (4) :257-266. 被引量：1
-
3Schwarzenberger P, Huang W, Ye P, et al. Requirement of endogenous stem cell factor and granulocyte-colony-stimulating factor for IL-17-mediated granulopoiesis [ J ]. J Immunol , 2000, 164 ( 9 ):4783-4789. 被引量：1
-
4Antonysamy MA, Fanslow WC, Fu F, et al. Evidence for a role of IL-17 in organ allograft rejection:IL-17 promotes the functional differentiation of dendritic cell progenitors[J]. J Inmunol, 1999,162( 1 ) :577-584. 被引量：1
-
5Jovanovic DV, Di Battista JA, Martel-Pelletier J, et al. IL-17 stimulates the production and expression of proinflammatory cytokines,IL-1 beta and TNF-alpha, by human macrophages[J]. J Immunol,1998,160(7 ) :3513-3521. 被引量：1
-
6Woltman AM, de Haij S, Boonstra JG, et al. Interleukin-17 and CD40-ligand synergistically enhance cytokine and chemokine production by renal epithelial cells [ J ]. J Am Soc Nephrol, 2000,11( 11 ) :2044-2055. 被引量：1
-
7Luzza F, Parrello T, Monteleone G, et al. Up-regulation of IL-17 is associated with bioactive IL-8 expression in Helicobacter pylori-infected human gastric mucosa[ J ]. J Immunol ,2000,165 (9) :5332-5337. 被引量：1
-
8Loong CC, Hsieh HG, Lui WY, et al. Evidence for the early involvement of interleukin 17 in human and experimental renal allograft rejectiou [ J ]. J Pathol, 2002,197 ( 3 ) :322-332. 被引量：1
-
9Hoshiro H, Laan M, Sjostrand M, et al. Increased elastase and myeloperoxidase activity associated with neutrophil recruitment by IL-17 in airway in vivo[J]. J Allergy Clin Immunol, 2000,105(1 pt1 ) :143-149. 被引量：1
-
10Ye P, Garvey PB, Zhang P, et al. Interleukin-17 and lung host defense against Klebsiella pneumoniae infection[J]. Am J Respir Cell Mol Biol,2001,25 ( 3 ) :335-340. 被引量：1
共引文献6
-
1刘启祥(综述),曹林升(综述),唐松喜(综述).IL-17在前列腺增生中的作用[J].国际泌尿系统杂志,2009,29(6):782-785.
-
2张薇,高红梅,叶贤龙,于艺雪,刘铭瑶,王文飞,任桂萍,李德山.小鼠白细胞介素17A的克隆、表达及活性鉴定[J].中国免疫学杂志,2010,26(9):783-786.
-
3孙阳,谷学佳,叶贤龙,徐黎明,陈睿,任桂萍,王秋颖,丁良军,李德山.一株中和人IL-17免疫活性的单克隆抗体的制备[J].免疫学杂志,2011,27(7):606-609.
-
4王群锁,李响,王涛,孙振芝,操海洲.IL-17在小鼠肾脏缺血再灌注损伤表达的变化及意义[J].临床泌尿外科杂志,2015,30(3):254-257. 被引量：3
-
5彭双凤,田鑫,王兴,廖金花,徐丽丽,李林.基于网络药理学探讨金叶拜毒颗粒抗新冠病毒的作用机制[J].中国民族民间医药,2021,30(3):19-27.
-
6姜伟光,党永康,杨柳,姜学超,乌兰.白细胞介素与深静脉血栓形成关系的研究进展[J].血管与腔内血管外科杂志,2022,8(5):573-576. 被引量：2
-
1刘朝奇,刘士德,中国医学科学院基础医学研究所.新一代疫苗——短肽疫苗的研究[J].微生物学免疫学进展,1998,26(2):69-72. 被引量：1
-
2刘朝奇.短肽疫苗─—人类疫苗的最后目标[J].三峡大学学报（人文社会科学版）,1998,21(1):100-102.
-
3樊娟,徐功立.粒细胞集落刺激因子及其受体[J].临床血液学杂志,1999,12(3):138-140. 被引量：23
-
4彭程,黎纬民,马艳萍,胡中波,程范军,刘凌波,邹萍.血管紧张素Ⅱ对脐血CD34^+细胞体外扩增的作用[J].中国实验血液学杂志,2003,11(3):227-229. 被引量：7
-
5时红波,姜昌富,李天群,潘虹,魏兰英,朱晓华,雷家慧.应用噬菌体十二肽库筛选卫氏并殖吸虫抗原模拟表位[J].中国寄生虫病防治杂志,2004,17(1):5-8. 被引量：1
-
6陶方方,王新军,刘丰,王慧,孙新娟,王勇,苏川,吴海玮,张兆松.日本血吸虫磷酸丙糖异构酶Th1型表位的免疫学鉴定[J].中国病原生物学杂志,2008,3(4):266-271. 被引量：1
-
7龙剑,谢红付,施为.抗TNF-α单克隆抗体对噬菌体随机12肽库的筛选[J].医学临床研究,2003,20(4):248-251.
-
8王慧,陶方方,孙新娟,刘丰,王勇,苏川,吴海玮,张兆松.日本血吸虫22.6kDa膜相关蛋白Th1型表位的免疫学鉴定[J].中国血吸虫病防治杂志,2009,21(1):11-14.
-
9朱凤臣,蒋电明,祁小桐,李维朝.低剂量LPS对PC12细胞抗氧化能力的影响[J].中国免疫学杂志,2011,27(5):430-433. 被引量：2
-
10杨小冬,刘福坤,许哲,陈彻,吴晓宇,李刚,黎介寿.G-CSF受体及其mRNA在结直肠癌和其附近正常黏膜中的表达[J].解放军医学杂志,2005,30(2):149-152. 被引量：6
