摘要
目的:分析常规剂量雷公藤多苷辅助治疗慢性肾小球肾炎的可行性及安全性。方法:将86例慢性肾小球肾炎患者按照随机数表法分为观察组和对照组,每组43例,对照组采用小剂量雷公藤多苷联合加味六味地黄汤进行治疗,观察组采用常规剂量雷公藤多苷联合加味六味地黄汤进行治疗。观察两组患者治疗前、后24hUprV、Ccr等肾功能指标以及临床疗效,并对结果进行分析比较。结果:治疗后观察组患者的24hUprV、Scr、BUN明显低于对照组,Ccr明显高于对照组;观察组患者的显效率明显高于对照组,差异均具有统计学意义(P<0.05)。结论:常规剂量雷公藤多苷辅助治疗慢性肾小球肾炎可以显著改善患者肾功能,效果良好,适合临床长期推广应用。
Objective：To analyze the feasibility and safety of conventional dose Tripterygium glycosides assisted treatment of chronic glomerulonephritis.Methods：86cases of patients with chronic glomerulonephritis,according to a random number table,they were divided into observation group and control group.The control group were used small doses Tripterygium glycosides joint Liu wei di huang tang treatment,the observation group were used conventional dose Tripterygium glycosides joint Liu wei di huang tang treatment.Observed and compared the two groups with 24 hUprV,Ccr,Scr,BUN of renal function and clinical efficacy.Results：After treatment,the observation group were 24 hUprV,Scr,BUN was significantly lower than the control group,Ccr significantly higher than the control group;The efficiency of the observation group were significantly higher than the control group,the differences were statistically significant（P〈0.05）.Conclusion：Conventional dose Tripterygium glycosides assisted treatment of chronic glomerulonephritis can significantly improve renal function,has good effect,and it is suitable for long-term clinical application.
出处
《医学理论与实践》
2015年第2期145-146,共2页
The Journal of Medical Theory and Practice
关键词
雷公藤多苷
加味六味地黄汤
慢性肾小球肾炎
Tripterygium glycosides
Liu wei di huang tang
Chronic glomerulonephritis
