摘要
微分子核糖核酸(MicroRNA,miRNA)是一类长度大约为22个核苷酸的非编码的单链RNA小分子,参与基因转录后水平的调控。miRNA通过调节与皮肤肿瘤增殖、侵袭、转移等相关的基因表达,参与皮肤肿瘤的发生、发展。本文就近年来对微分子核糖核酸在皮肤肿瘤研究的进展做一综述。
MicroRNA(miRNA) constitutes a group of small(21-23 nucleotide) noncoding RNAs that functional as posttranscriptional gene regulators, miRNA involved in the dermatoma development which have been suggested to play a vital role in operating to promote or suppress dermatoma proliferation, invasion and metastasis.This paper reviews recent research progresses of regulation effect of microRNA on dermatoma genes.
出处
《皮肤病与性病》
2015年第1期22-24,共3页
Dermatology and Venereology