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我院2013年住院患者抗菌药物使用强度分析 被引量:10

Analysis of AUD of Antibacterials in Inpatients of Our Hospital in 2013
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摘要 目的:为临床合理使用抗菌药物提供参考。方法:采用回顾性分析法,收集整理我院药剂科药品管理数据库和医院信息管理系统中2013年14 009例住院患者应用抗菌药物的数据,并对用药频度(DDDs)、使用强度(AUD)和日均费用(DDC)进行统计、分析。结果:2013年我院住院患者抗菌药物的总AUD为52.705 DDDs/(100人·天),AUD最大的前3类抗菌药物为头孢菌素类、喹诺酮类、青霉素类,其AUD值分别为25.363、9.278、4.166 DDDs/(100人·天)。DDC在150元以上的抗菌药物有注射用美罗培南、盐酸莫西沙星氯化钠注射液、注射用头孢甲肟。结论:我院抗菌药物总AUD低于国内医院平均水平,抗菌药物使用品种及DDC较合理,但仍存在抗菌药物应用过度、过于集中,部分医师偏爱应用广谱、价格昂贵抗菌药物等现象。 OBJECTIVE: To provide reference for clinical rational use of antibacterials. METHODS: By retrospective study, the date of 14 009 hospitalized patients with antibacterial drugs in the Dept. of pharmacy Drug administration database and hospital information management system in 2003 was collected , and DDDs, AUD and DDC were statistically analyzed. RESULTS: The AUD of inpatients in our hospital was 52.705 DDDs/(100 person, d) in 2013. Top 3 antibacterials in the list of AUD were cephalosporins, quinolones and penicillins with AUD values of 25.363,9.278 and 4.166 DDDs/(100 person, d) respectively. DDC of antibacterils were more than 150 yuan, including Meropenem for injection, Moxifloxacin hydrochloride and sodium chloride injection and Cefmenoxime for injection. RESULTS: The AUD of inpatients in our hospital was 52.705 DDD/( 100 person-d) in 2013. Top 3 antibacterials in the list of AUD were cephalosporins, quinolones and penicillins with the AUD values of 25.363,9.728 and 4.166 DDDs/(100 person, d), DDC of antibacterils were more than 150 yuan, including meropenem for injection, Moxifloxacin hydrochloride and sodium chloride injection and Cefmenoxime for injection. CONCLUSIONS: AUD of antibacterials in our hospital is lower than national average level and the strategies of antibacterials and DDC is reasonable. But there still are some problems as overuse of antibacterial, centralized use, and expensive broad-spectrum antibacterials usually used by some doctors.
作者 李静 孙秀英
出处 《中国药房》 CAS 北大核心 2015年第5期582-584,共3页 China Pharmacy
关键词 抗菌药物 限定日剂量 使用强度 日均费用 用药频度 Antibacterial drugs DDD AUD DDC DDDs
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