摘要
目的:观察人工流产术后口服复方短效口服避孕药(优思明)和放置宫内节育器(安舒环)避孕的临床效果和安全性。方法:人工流产后健康孕妇292例,按照随机数字法随机分两组,每组146例,安舒环组人工流产术后放置安舒环避孕;优思明组人工流产术后当日口服优思明,每日1片,连服21d为1个疗程,停药后月经来潮,在月经来潮第5天开始服用下一疗程,共5个疗程。两组均随访1年,观察两组对象术后出血量及时间、阴道分泌物及子宫内膜厚度、月经恢复正常周期时间及不良反应情况。结果:优思明组术后出血时间为(4.35±2.22)d,低于安舒环组的(5.87±2.30)d,差异具有统计学意义(t=5.7455,P<0.05);优思明组阴道分泌物正常者(95.2%),高于安舒环组(78.1%),差异有统计学意义(χ2=18.496,P<0.05);优思明组的子宫内膜厚度优于安舒环组(t=18.125,P<0.05);且月经恢复时间短于安舒环组(t=40.257,P<0.05)。两组避孕失败率(分别为1.4%、2.8%)差异无统计学意义(χ2=0.681,P>0.05);术后1个月不良反应发生率优思明组低于安舒环组(χ2=5.508,P<0.05)。结论:人工流产术后口服优思明可作为首选避孕方法,其可显著改善对象术后情况,有助于对象机体功能的恢复;而放置安舒环可作为长期避孕的首选方式。
Objective： To explore the clinical effects and safety of short-acting oral contraceptive （Yasmin） use and medicated-γintrauterine device insertion after artificial abortion. Methods： A total of 292 healthy pregnant women who underwent artificial abortion were recruited and randomly divided into two groups （146 women in each group）. Women in IUD group were inserted medicated-γintrauterine device. And those in Yasmin group were given one tablet of Yasrain on the operation day for 21-day cycle as well as five courses of treatment. Postoperative vaginal bleeding amount and duration, vaginal discharge, endometrial thickness, menstrual recovery time and adverse reactions of the two groups were evaluated. Results： The duration of vaginal bleeding of Yasmin group was （4.35±2.22） d, significantly lower than that in IUD group [（5.87±2.30） d, t=5.7455, P〈 0.05）]. The rate of normal vaginal discharge in Yas min group was 95.2%, significantly higher than that in IUD group （78.1%）x^2=18.496, P〈0.05）. Endometrial thickness of Yasmin group was more than that of IUD group （t = 18.125, P〈0.05）. And the menstrual recovery time of Yasmin group was shorter than that of IUD group （t =40.257, P〉0.05）. Contraceptive failure rates of the two groups were 1.4% and 2.8% respectively, showing no statistically significant difference （x^2=0.681, P〉0.05）. The incidence of adverse reactions one month after the operation in Yasmin group was significantly lower than that in IUD group （x^2= 5. 508, P〈0.05）. Conclusion.. Yasmin could be used as the preferred method after abortion, which signif- icantly improves patienfs postoperative situation, and helps the body function to recover, while IUD insertion could serve as a preferred way of long-term contraception.
出处
《中国计划生育学杂志》
2015年第2期109-111,共3页
Chinese Journal of Family Planning
关键词
优思明
人工流产术
临床疗效
避孕
安舒环
Yasmim Artificial abortiom Clinical effect
Contraception
Medicated-γ intrauterine device
