摘要
目的了解患儿呼吸道感染肺炎支原体（Mp）培养阳性率及药敏特点,为临床诊断及治疗提供依据。方法对2013年2月-2013年7月1023例呼吸道感染患儿送检标本进行Mp培养及药敏试验,数据采用SPSS13.0统计软件进行处理。结果 1023例呼吸道感染患儿送检标本Mp培养阳性354例,阳性率为34.6%;其中急性支气管炎Mp培养阳性率最高,达65.0%,其次是上呼吸道感染和毛细支气管炎,阳性率分别为50.0%和45.9%,其他呼吸道疾病Mp培养阳性率为20.0%-40.0%,上呼吸道感染和肺炎患儿Mp阳性率比较,差异有统计学意义（P〈0.01）;Mp对多西环素敏感率最高为99.2%,对大环内酯类药物的敏感性相对较低,对罗红霉素、红霉素的敏感率分别为68.6%、66.1%。结论对发病初期患儿及早做Mp培养及药敏,做到早发现、早诊断、早治疗,避免并发症的发生,并根据药敏试验结果选择合理的抗菌药物。
OBJECTIVE To investigate the distribution and drug resistance of Mycoplasma pneumoniae in respiratory tract infections,so as to provide evidence for clinical prevention of infections and reasonable use of antibiotics.METHODS Specimens from a total of 1023 patients with respiratory tract infections from Feb.2013 to Jul.2013 were delivered for M.pneumoniae culture and drug sensitivity test.Data were processed with the SPSS13.0statistical software.RESULTS The 354 specimens were positive with M.pneumoniae among the 1 023specimens（34.6%）.The highest positive rate of M.pneumonia was seen in acute bronchitis（65.0%）,followed by upper respiratory infections（50.0%）and capillary bronchitis（45.9%）,and other respiratory diseases（20.0%-40.0%）.There was difference in the positive rate between children with upper respiratory tract infections and children with pneumonia（P 〈0.01）.The drug sensitive rate to doxycycline was the highest（99.2%）,while the sensitivity to macrolides was relatively low,and the sensitivity to roxithromycin and erythromycin was 68.6%,and 68.6%,respectively.CONCLUSION The M.pneumonia culture and the drug susceptibility testing as early as possible as well as early detection,early diagnosis and early treatment can avoid the complications and clinicians should achieve reasonable use of antibiotics according to the drug susceptibility testing result.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2015年第4期756-757,763,共3页
Chinese Journal of Nosocomiology
基金
浙江省金华市科技局基金资助项目(2010-3-031)
关键词
呼吸道感染
肺炎支原体
药敏试验
Respiratory tract infection
Mycoplasma pneumoniae
Drug sensitivity testing
