摘要
目的了解鲍曼不动杆菌的临床分布及对抗菌药物的耐药性,为临床治疗鲍曼不动杆菌感染提供合理用药的依据。方法收集临床标本中分离出的162株鲍曼不动杆菌,对其分布情况以及16种抗菌药物的药敏结果进行统计分析。结果标本分布以痰液为主(75.3%);ICU病区检出率最高(49.3%),其中多重耐药菌占81.2%(65/80);ICU病区鲍曼不动杆菌多重耐药现象严重,对16种常用抗菌药物的耐药率明显高于非ICU病区,差异具有统计学意义(P<0.01),妥布霉素、阿米卡星和头孢哌酮/舒巴坦的耐药率相对较低。结论加强多重耐药菌株的监测和ICU病区的消毒隔离,对于预防和控制医院感染具有重要意义。
Objective To understand the clinical distribution of Acinetobacter baumannii and its resistance to antibacterial drugs in order to provide reference for clinical rational drug use in the treatment of Acinetobacter baumannii infection.Methods 162 strains of Acinetobacter baumannii isolated from clinical specimens were collected and performed the statistical analysis on the dis-tribution and the sensitivity to 16 kinds of antibacterial drugs.Results The specimen distribution was dominated by sputum speci-mens（75.3%）.The ICU ward had the highest detection rate（49.3%）,in which,multidrug resistant strains accounted for 81.2%（65/80）;the strains from ICU had the serious multidrug resistance,their resistance rates to 16 kinds of commonly used antibacterial drugs were significantly higher than those the strains isolated from other wards,the difference had statistical significance（P 〈0.01）.The resistance rates of Acinetobacter baumannii to tobramycin,amikacin and cefperazone/sulbactam were relatively lower. Conclusion Strengthening the monitoring of multidrug resistant Acinetobacter baumannii strains and the sterilization and isolation of ICU ward has the important significance to prevent and control nosocomial infection.
出处
《国际检验医学杂志》
CAS
2014年第23期3224-3225,共2页
International Journal of Laboratory Medicine
关键词
鲍曼不动杆菌
重症监护
耐药性
Acinetobacter baumannii intensive care unit drug resistance
