摘要
目的通过对苦碟子注射液开展前瞻性、非干预性的医院集中监测,探索药品重点监测的实践。方法采取医院集中监测的方法对苦碟子注射液进行主动监测,监测时间为2012年6月-2014年3月,监测范围为吉林省辖区内7家医疗卫生机构住院患者,对观察样本进行流行病学统计分析。结果共观察2 986例有效病例,观察对像中,男女比例接近1：1;用药患者中50岁以上的中老年人居多,占78.57%;药物主要应用于神经内科和心血管内科;用药适应证、给药途径、给药剂量基本符合说明书指导要求;本次研究中不良反应有皮疹、呼吸困难、肿胀,均为一般不良反应,无需特殊处理,停药即可痊愈。结论苦碟子注射液重点监测采取医院集中监测的方法易于组织实施,该方法用于住院患者用药的重点监测可以节省成本,并提高效率。
Objective Through the development of intensive hospital monitoring of Kudiezi injection which is prospective and non-interventional, explore the practice of drug intensive monitoring. Methods Adopt the intensive hospital monitoring of Kudiezi injection at seven hospitals in Jilin province from June 2012 to March 2014, and make an epidemiological statistical analysis for the results of samples. Results We collected 2 986 effective questionnaires, the sex ratio is nearly equal, and 78.57% patients are over 50 years old. Kudiezi injections are mostly used in neurology and cardiology. The indications, administration and dosage are consistent with the drug instruction. The symptoms of adverse reactions are rash, difficult breathing and swelling, which are all common, and need nothing special treating, just stop using the drugs to recover. Conclusion The intensive hospital monitoring ofkudiezi injection is easy to organize and implement. This method will save the cost and increase efficiency if it can be used in intensive monitoring.
出处
《中国药物警戒》
2014年第12期753-756,759,共5页
Chinese Journal of Pharmacovigilance
关键词
苦碟子注射液
临床应用
重点监测
不良反应
Kudiezi injection
clinical application
intensive monitoring
adverse drug reaction
