摘要
目的探讨Ahmed青光眼减压阀植入术对角膜内皮细胞的影响。方法对开角型青光眼40例（42眼）行Ahmed减压阀植入术，术后随访观察1、3、6、12个月，手术前后进行角膜内皮细胞密度和细胞形态学的检测。结果术前平均角膜内皮细胞密度（2586．84±386．30）个／mm^2，术后1、3、6、12个月分别为（2545．90±396．74）个／mm^2，（2548．75±410．36）个／mm^2，（2560．20±379．15）个／mm^2和（2498．20±402．23）个／mm^2，彼此间差异均无统计学意义。细胞形态、平均细胞面积、最小细胞面积、最大细胞面积、六角形细胞百分数、细胞面积标准差、细胞面积变异系数术前术后差异均无统计学意义。结论一般情况下，Ahmed减压阀植入术不会引起角膜内皮细胞丢失或其它不良影响。
Objective To observe the changes of corneal endothelial cell after Ahmed glaucoma valve implantation. Methods Forty-two eyes of 40 patients of primary open-angle glaucoma had accepted cellular morphology and corneal endothelial cell density examination with non-contact corneal endothelial microscope before and after Ahmed glaucoma valve implantation. The follow-up time was 1, 3, 6, and 12 month after surgery. Results The mean endothelial cell density was （ 2586.84±386.30） cells/mm^2 before surgery, and 1, 3, 6, and 12month after surgery, the mean endothelial cell density was （2545.90 ±396.74） cells/mm^2 , （2548.75± 410.36 ） cells/mm^2, （ 2560.20± 379.15 ） cells/mm^2, and （ 2498.20 ±402.23 ） cells/mm^2 respectively. The differences was not statistically significant between before and after surgery on cellular morphology, the mean cellular area, the minimun and the maximum cellular area, the percentage of hexagonal cell, the standard deviation and coefficient variation of cellular area respectively （ P 〉 0.05 ）. Conclusion Under usual condition, Abmed glaucoma valve implanting has no harmful effect on corneal endothelial cell of patients with primary open-angle glaucoma.
出处
《中华眼外伤职业眼病杂志》
2015年第1期51-52,共2页
Chinese Journal of Ocular Trauma and Occupational Eye Disease
