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六味地黄汤改善肝肾阴虚型骨质疏松症下肢肌力随机平行对照研究 被引量:2

Six taste glutinous rehmannia decoction can improve the liver kidney yin deficiency type osteoporosis, muscle strength of lower limbs of random parallel control
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摘要 [目的]观察六味地黄汤改善肝肾阴虚型骨质疏松症下肢肌力。[方法]使用随机平行对照方法,将60例住院及门诊患者按病志号抽签/就诊顺序号方法随机分为两组。对照组30例阿法骨化醇,0.5ug/次,每晚1次,口服。治疗组30例六味地黄汤(熟地黄25g,山药30g,山茱萸15g,茯苓10g,牡丹皮15g,泽泻10g,骨碎补15g,续断15g,淫羊藿30g),1剂/d,水煎400m L,早晚口服。连续治疗3个月为1疗程。观测临床症状、不良反应。治疗1疗程,判定疗效。[结果]治疗组临床控制12例,显效10例,有效6例,无效2例,总有效率93.33%。对照组临床控制6例,显效12例,有效4例,无效8例,总有效率73.33%。治疗组疗效优于对照组(P<0.05)。[结论]六味地黄汤改善肝肾阴虚型骨质疏松症下肢肌力,疗效满意,无副作用,值得推广。 [Objective] To observe the six tastes glutinous rehmannia decoction can improve the liver kidney yin deficiency type osteoporosis, muscle strength of lower limbs. [Methods] Using random parallel control method, 60 cases of inpatient and outpatient patients according to disease Zhihao draw / visiting sequence were randomly divided into two groups, method. The control group of 30 cases of alfacalcidol, 0.5ug/ times, every night 1, oral. The treatment group 30 cases of Six Ingredient Rehmannia Decoction, Radix Rehmanniae Preparata 25 g, 30 g yam, Cornus officinalis 15 g 10g, Poria, cortex moutan Rhizoma alismatis Rhizoma Drynariae 15 g, 10 g, 15 g, 15 g, 30 g of Radix dipsaci, epimedium, 1 agent /d, Decoction 400 m L, sooner or later oral. 3 months of continuous treatment for 1 courses. Observation of clinical symptoms and adverse reaction. 1 courses of treatment, curative effect. [Result] The treatment of clinical control group of 12 cases, 10 cases markedly effective, effective 6 cases, invalid 2 cases, the total efficiency of 93.33%. Clinical control group of 6 cases, 12 cases markedly effective, effective 4 cases, invalid 8 cases, the total efficiency of 73.33%. The efficacy of the treatment group was better than that of the control group(P〈0.05).[Conclusions]The six tastes glutinous rehmannia decoction can improve the liver kidney yin deficiency type osteoporosis, muscle strength of lower limbs, satisfactory curative effect, no side effect, is worth promoting.
作者 金成辉
出处 《实用中医内科杂志》 2014年第12期8-9,106,共3页 Journal of Practical Traditional Chinese Internal Medicine
关键词 骨质疏松症 骨痿 下肢肌力 肝肾阴虚 六味地黄汤 中医药治疗 随机平行对照研究 Osteoporosis muscle strength of lower limbs Yin deficiency of liver and kidney the six tastes glutinous rehmannia Decoction Chinese medicine therapy randomized controlled study
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