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异甘草酸镁注射液治疗急性黄疸型病毒性肝炎临床疗效探讨 被引量:4

Observation on the Clinical Effect of Magnesium Isoglycyrrhizinate Injection in the Treatment of Acute Icteric Viral Hepatitis
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摘要 目的探讨异甘草酸镁注射液治疗急性黄疸型病毒性肝炎的临床效果。方法从该院2012年6月—2014年3月接收并治疗的急性黄疸型病毒性肝炎患者中选取84例进行回顾性分析,随机分为观察组与对照组,每组42例,对照组行护肝退黄综合治疗,观察组在对照组治疗基础上加用异甘草酸镁注射液治疗,观察两组患者治疗效果、肝功能变化。结果观察组治疗总有效率为92.86%,对照组治疗总有效率为67.65%,观察组治疗效果显著优于对照组;观察组ALT、AST、TBLL指数均明显低于对照组,观察组肝功能情况显著优于对照组,观察组不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。结论在急性黄疸型病毒性肝炎的治疗过程中,在常规治疗基础上加用异甘草酸镁能有效提高治疗效果,减少不良反应发生,值得临床应用和推广。 Objective To investigate the clinical effect of Magnesium Isoglycyrrhizinate Injection in the treatment of acute icteric viral hepatitis. Methods 84 patients with acute icteric viral hepatitis admitted in our hospital from June 2012 to March 2014 were selected for retrospective analysis. The patients were randomly divided into the observation group and the control group with 42 cases in each. The control group was treated by comprehensive treatment for protecting liver and eliminating jaundice, and the observation group was treated by Magnesium Isoglycyrrhizinate Injection based on the treatment given to the control group. And the treatment effect, changes of liver function of the two groups were observed. Results The total effective rate was 92.86% in the observation group, 67.65% in the control group, the treatment effect of the observation group was significantly better than that of the control group; the ALT, AST, TBLL index and the incidence of adverse reactions of the observation group was obviously lower than that of the control group, respectively, the liver function was much better than that of the control group, the differences were statis-tically significant(P〈0.05). Conclusion In the treatment of acute icteric viral hepatitis, conventional treatment combined with Magnesium isoglycyrrhizinate can effectively improve the therapeutic effect, reduce the incidence of adverse reactions, so it is worthy of clinical application and promotion.
作者 陈健儿
出处 《中外医疗》 2014年第32期9-10,共2页 China & Foreign Medical Treatment
关键词 急性黄疸型肝炎 异甘草酸镁 治疗效果 Acute icteric hepatitis Magnesium isoglycyrrhizinate Therapeutic effect
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