摘要
Purinergic receptors are among the first cell surface receptors expressed during embryonic development （Burnstock and Ulrich, 2011）. These are characterized based on their pharmacological properties of being activated by adenosine or purine/pyrimidine nucleotides as P1 and P2 receptors. P2 receptors are further classified by their structure as P2Y metabotropic and P2X ionotropic receptors.
Purinergic receptors are among the first cell surface receptors expressed during embryonic development （Burnstock and Ulrich, 2011）. These are characterized based on their pharmacological properties of being activated by adenosine or purine/pyrimidine nucleotides as P1 and P2 receptors. P2 receptors are further classified by their structure as P2Y metabotropic and P2X ionotropic receptors.
基金
support from Fundacao de Amparo à Pesquisa do Estado de Sao Paulo (FAPESP)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
the Provost’s Office for Research of the University of Sao Paulo, Grant number: 2011.1.9333.1.3 (NAPNA-USP)
support from the German Research Council (IL 20/182, RI 2092/1-2, IL 20/21-1)
the Sino-German Centre for the Support of Science (GZ 919)
