摘要
目的：分析发生医院鲍曼不动杆菌血液感染的危险因素，为制定其防治策略提供依据。方法采用回顾性调查方法，收集2010～2013年本院住院诊断为鲍曼不动杆菌血液感染患者临床资料，进行病例对照研究，分析发生医院鲍曼不动杆菌血液感染的危险因素。结果医院鲍曼不动杆菌血液感染的主要危险因素为混合细菌感染，APACHEⅡ＞20，深静脉留置，抗生素应用天数≥2周，年龄＞60岁，抗生素应用种类数量≥3，其相对危险度分别为4．226、3．517、3．354、2．428、1．771及1．123。结论积极治疗原发病，缩短住院时间，严格执行消毒隔离措施，防止出现交叉感染，合理使用广谱抗生素尤其是严格掌握碳青霉烯类的适应证，可预防和减少鲍曼不动杆菌血液感染的产生。
Objective To analyze risk factors of in-hospital Acinetobacter baumannii （ AB ） blood infection and to provide basis for its prevention and control strategy .Methods Retro-spective survey method was adopted .Clinical data of in-hospital patients diagnosed with AB blood infection from 2010 to 2013 was collected , risk factors of in-hospital AB blood infections were analyzed by case-control study .Results Major risk factors of in-hospital AB blood infec-tions were as follows：mixed bacterial infection , APACHEⅡ＆gt;20 , deep venous catheter , anti-biotics use for over 2 weeks, over 60 years old, and uses of over 3 types of antibiotics .The hazard degree was 4.226, 3.517, 3.354, 2.428, 1.771 and 1.123 respectively.Conclusion Active treatment of primary disease , shortened in-hospital stay , strict disinfection and isola-tion measures for preventing the occurrence of cross infections , the rational use of broad-spec-trum antibiotics, and especially strict control over Carbapenem indication can prevent and less-en the occurrence of AB blood infections .
出处
《哈尔滨医科大学学报》
CAS
北大核心
2014年第6期513-515,共3页
Journal of Harbin Medical University
关键词
鲍曼不动杆菌
菌血症
危险因素
Acinetobacter baumannii
bacteremia
risk factors
