摘要
目的分析不同剂量间苯三酚对产妇心理、产程时间及胎儿健康的影响。方法将2012年6月到2013年6月收治的120例无妊娠综合征及并发症的健康初产妇分为3个组:A组给予静脉注射80mg间苯三酚,B组给予静脉注射120mg间苯三酚,C组给予静脉注射160mg间苯三酚,每组各40例。观察并比较3个组产妇的心理状态、用药后宫口开大情况、产程时间、剖宫产率、新生儿窒息率、羊水污染率、产后出血发生率及不良反应情况。结果 3个组产妇产后SAS评分比较,差异有统计学意义(t=2.514,3.522,4.695,P<0.05);用药后,3个组产妇第一产程时间比较,差异有统计学意义(P<0.05),第二产程比较,差异无统计学意义(P>0.05);用药后40min和2h3个组产妇宫口开大情况比较,差异有统计学意义(P<0.05);3个组产妇剖宫产率、新生儿窒息率、羊水污染率、产后出血发生率比较差异无统计学意义(χ2=0.313,2.051,0.120,0.287,均P>0.05);3个组不良反应发生率比较差异无统计学意义(χ2=0.959,P>0.05)。结论在分娩过程中规范静脉注射160mg间苯三酚即可达到临床目的,明显促进产程、改善产妇焦虑状态、保证母婴健康,安全高效,且不良反应少,值得临床进一步研究推广。
Objective To analyze the effects of different doses of phloroglucin on parturient psychology ,birth process and fetal health .Methods 120 healthy primiparas without pregnancy syndrome and complications in our hos‐pital from June 2012 to June 2013 were randomly divided into three groups ,40 cases in each group .The group A ,B and C received the intravenous injection of phloroglucin 80 mg ,120 mg and 160 mg respectively .The psychological status ,cervical dilitation after medication ,duration of labor ,cesarean section rate ,neonatal asphyxia rate ,amniotic flu‐id contamination rate ,occurrence rate of postpartum hemorrhage and adverse reaction situation were observed and compared among the three groups .Results The difference of SAS scores among three primiparas groups was statisti‐cally significant （t=2 .514 ,3 .522 ,4 .695 ,P〈0 .05）;the time of the first stage of labor after treatment had statistical‐ly significant differences among the three groups （P〈0 .05） ,the time of second stage of labor had no statistically sig‐nificant difference among the three groups（P〉0 .05）;the cervical dilation situation at 40 min and 2 h after medication showed the statistical difference among the three groups （P〈 0 .05）;the cesarean section rate ,neonatal asphyxia rate ,amniotic fluid contamination rate and postpartum hemorrhage rate had no statistically significant differences a‐mong the three groups （χ^2 =0 .313 ,2 .051 ,0 .120 ,0 .287 ,P〉0 .05）;the occurrence rate of adverse reactions in the three groups showed no statistically significant difference （χ^2 =0 .959 ,P〉0 .05） .Conclusion During the delivery process ,the standardized intravenous injection of phloroglucin 160 mg can achieve the clinical purpose ,obviously pro‐mote the labor process ,improve the parturient′s anxiety state and ensure maternal and neonatal health with safety , high efficiency and less adverse reactions ,which is worthy of further clinical study .
出处
《检验医学与临床》
CAS
2015年第2期191-192,195,共3页
Laboratory Medicine and Clinic
关键词
间苯三酚
产妇
产程
胎儿
phloroglucin
parturient
labor process
fetus
