摘要
30名原发性高血压患者随机分为运动组和对照组.运动组进行24周有氧运动,对照组保持日常生活习惯不变.实验前后分别测定心率、血压、心率变异性(HRV)、血压变异性(BPV)和压力反射敏感性(BRS),探讨长期有氧运动对原发性高血压患者心血管自主神经功能的影响,以期为制定特异性的运动处方提供依据.结果发现,实验前,两组各指标均无显著性差异(P>0.05).实验后,组内与运动前比较,运动组安静心率(P<0.01)、收缩压(P<0.05)和舒张压(P<0.05)下降,HRV总功率(TP)、高频功率(HF)和标准化高频功率(HFn)升高(P<0.01),HRVLF/HF降低(P<0.01),BPV低频功率(LF)和标准化低频功率(LFn)降低(P<0.01),BRS升高(P<0.01),对照组所有指标均无显著性变化(P>0.05);组间比较,运动组心率(P<0.01)、收缩压(P<0.05)和舒张压(P<0.05)均低于对照组,HRV TP、HF、HFn和BRS高于对照组(P<0.01),HRV LF/HF(P<0.01)、BPV LF和LFn(P<0.01)均低于对照组.结果提示,长期有氧运动可降低原发性高血压患者安静心率和血压,其机制可能与心血管自主神经功能改善有关,即心交感和交感缩血管神经调制减弱,迷走神经张力和压力反射功能增强,交感―迷走平衡呈现迷走优势.
Thirty essential hypertension patients were randomly divided into exercise group and control group.Subjects of exercise group performed 24-week aerobic exercise while control group maintained their routine living habit.Heart rate,blood pressure,heart rate variability （HRV）,blood pressure variability （BPV） and baroreflex sensitivity （BRS） were determined before and after the experiment to explore the effects of long-term aerobic exercise on cardiovascular autonomic nervous function in essential hypertension patients in order to provide evidence for special exercise prescription.The results were as follows：before test,all indicators of both groups had no significant difference （P＞0.05）.After test,heart rate （P＜0.01）,SBP （P＜0.05） and DBP （P＜0.05） decreased,HRV total power （TP）,high frequency （HF） and normalized high frequency （HFn） raised （P ＜ 0.01）,HRV LF/HF lowered （P＜0.01）,BPV low frequency （LF） and normalized low frequency （LFn） descended （P＜0.01）,and BRS heightened （P＜0.01） in exercise group; there no significant differences of all indexes in control group （P＞0.05）; Compared between groups,heart rate （P＜0.01）,SBP （P＜0.05） andDBP （P＜0.05） were lower,HRV TP,HF,HFnand BRS were higher,HRV LF/HF （P＜0.01）,BPV LF and LFn （P＜0.01） were lower in exercise group than in control group.The results suggested that long-term aerobic exercise training effectively reduced resting heart rate and blood pressure and the mechanism was related with improvement of cardiovascular autonomic nervous function including decreased sympathetic nervous system （cardiac sympathetic nerve and sympathetic vasoconstrictive nerve） modulation,increased vagal tone and baroreflex sensitivity and improved sympathovagal balance.
出处
《河南大学学报（自然科学版）》
CAS
2015年第1期73-77,共5页
Journal of Henan University:Natural Science
基金
河南省基础与前沿技术研究计划项目(142300410242)
关键词
原发性高血压
血压
有氧运动
心血管系统
自主神经
essential hypertension
blood pressure
aerobic exercise
cardiovascular system
autonomic nerve
