摘要
目的了解甲状腺乳头状微灶癌(PTMC)气管旁淋巴结转移情况,探讨临床颈淋巴结阴性(c N0)PTMC患者发生Ⅵ区淋巴转移的危险因素。方法回顾性分析行患侧甲状腺根治性切除+颈Ⅵ区淋巴清扫术的120例c N0PTMC患者临床资料。根据术后病理检查分为Ⅵ区淋巴结转移组(40例)和未转移组(80例),并对可能的危险因素进行分析研究。结果 PTMC颈Ⅵ区淋巴结转移率为33.3%,单侧癌灶部位(P<0.05)、甲状腺包膜侵犯(P<0.05)、单侧多灶性PTMC(P<0.01)为Ⅵ区淋巴结转移的危险因素。结论 c N0PTMC有较高的颈部中央组淋巴结转移率,在切除甲状腺的同时清扫颈Ⅵ区的淋巴结是十分必要的,尤其有相关危险因素者。
Objective To analyze the risk factors of central compart-ment lymph node （ CCLN） metastasis in papillary thyroid micro carcino-ma （ PTMC ） without clinical cervical lymph node metastasis （ cN0 ） , according to the general situation of paratracheal lymph node metastasis in PTMC.Methods Clinical data of 120 PTMC （ cN0 ） patients who underwent radical thyroidectomy and CCLN dissection were retrospective-ly analyzed.Patients were divided into CCLN positive group （ 40 cases ） and CCLN negative group （80 cases） according to postoperative pathology results, and the risk factors were analyzed.Results The CCLN metasta-sis rate of PTMC was 33.3%.Position （ P〈0.05 ） , capsular invasion （P〈0.05）, multifocal PTMC （P〈0.01） were the risk factors of CCLN metastasis.Conclusion The （ cN0 ） PTMC has a high rate of pathologi-cal CCLN metastasis.It is imperative to conduct the thyroidectomy with ipsilateral level Ⅵ lymph node dissection in PTMC patients , especially those with related risk factors.
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2015年第2期96-98,共3页
The Chinese Journal of Clinical Pharmacology
