摘要
多发性大动脉炎(TA)是一种累及主动脉及其主要分支以及肺动脉的少见的、慢性血管炎,常见于生育期女性。目前诊断TA活动期主要依靠全身表现、典型缺血症状、急性期实验室指标升高、以及血管壁影像特征。然而,鉴于本病活动期是慢性的、无痛的病程,并且缺乏特征性实验室和影像学检查结果,故对TA疾病活动期以及所带来的机体损害的评估是不够的。两个最近推出的多系统临床评估工具—DEI.Tak和ITAS2010,似乎对评估TA疾病活动度以及所带来的机体损害有帮助。如何准确判断大动脉炎活动度,及时发现病情复发及准确掌握手术时机仍是当前临床工作中的难题。本文笔者就该方面的问题进行综述。
Takayasu’s arteritis（TA） is a rare chronic vasculitis involving the aorta and its main branches, as well as the pulmonary arteries, and occurs most frequently in women in childbearing age. Currently, the diagnosis for TA active stage depends on systemic manifestations, typical ischemic symptoms, elevated acute-phase responses, and angiographic features. However, the assessment for disease activity and TA-induced damage is insufficient due to its chronic, indolent disease course and lack of specific laboratory and imaging findings. Two recently introduced multi-systemic clinical assessment tools, DEI. Tak and the ITAS 2010, seem to be helpful in assessing the disease activity and damage of TA. How to accurately determine the disease activity, timely detection of disease recurrence and properly define the timing of surgery are still unsolved problems in current clinical practice. In this article, the authors address the issues of these concerns.
出处
《中国普通外科杂志》
CAS
CSCD
北大核心
2014年第12期1701-1706,共6页
China Journal of General Surgery
