摘要
目的探讨男性不育患者生殖激素水平与精子质量的相关性。方法 3 108例男性不育患者按世界卫生标准进行精液常规分析,根据精液分析结果分为对照组(精液正常)和4个研究组:A组(弱精子症)、B组(少精子症)、C组(少弱精子症)、D组(严重少精子症)。回顾性分析各组的生殖激素(FSH、LH、E2、PRL、T)水平。结果 4组的FSH和LH水平明显高于对照组(P<0.05),T和E2水平与对照组比较,差异均无统计学意义(P>0.05)。A组、C组的PRL水平明显高于对照组(P<0.01),B组、D组与对照组比较,差异无统计学意义(P>0.05)。D组的FSH水平增高者异常发生率高于其他各组(P<0.05)。结论精子质量与多种血清性激素尤其是FSH异常密切相关,精液分析联合血清生殖激素检测为临床治疗男性不育提供了重要依据。
Objective To investigate the relationship between sperm quality and reproductive hormone levels in infertile men.Methods According to the result of routine sperm analyses by WHO standard,3 108 infertile men was divided into control group（ normal sperm in number and activity） and four study groups： group A（ asthenospermia）,group B（ oligozoospermia）,group C（ oligozoospermia and asthenospermia）,group D（ severe oligozoospermia）. The level of serum hormones（ FSH,LH,E2,PRL,T） were retrospectively analyized in all groups. Results The level of serum FSH and LH of four study groups were significantly higher than those of control group（ all P〈 0. 05）,there was no significant difference in the level of serum E2 and T between every study group and control group,the level of serum PRL of group A and group C were significantly higher than that of control group（ all P〈 0. 01）,but there was no significant difference in the level of serum PRL between group B and group D with control group（ both P〉 0. 05）. The occurrence of the level of FSH above nomal in group D was significantly higher than that in all other groups（ all P〈 0. 05）. Conclusion Abnormal sperm is closely related with the abnormal level of a variety of reproductive hormones especially FSH,a semen analysis combined with reproductive hormones detected maybe provide an important basis for the clinical treatment of infertile men.
出处
《中国卫生检验杂志》
北大核心
2014年第23期3470-3471,3474,共3页
Chinese Journal of Health Laboratory Technology
关键词
精子质量
生殖激素
相关性
Sperm quality
Reproductive hormone
Relationship
