摘要
寻找安全、高效的基因递送载体一直是基因治疗领域的研究热点之一。本文对近年来PLGA作为递送载体及相关问题进行了综述。首先简述了PLGA纳米颗粒的性质及制备方法，然后对其作为递送载体的研究概况进行了探讨，最后指出了目前PLGA作为递送材料存在的问题，并对其前景进行了展望。
To explore safe and efficient gene delivery carriers is of the hot topic in the field of gene therapy.In this paper,research progress on PLGA nanoparticles as gene delivery carriers in the recent years were reviewed.We described the present research status in PLGA nanoparticles and their preparation method.Discussion indepth for the application of PLGA nanoparticles in biomedical research was also given in the article.Meanwhile,problems existing in PLGA nanoparticles as a delivery carriers were pointed out while its prospect was also proposed.
出处
《转化医学电子杂志》
2014年第6期155-158,共4页
E-Journal of Translational Medicine
基金
国家自然科学基金（U1404824）
河南科技大学博士启动基金（09001635）
河南科技大学青年科学基金（2013QN44）
河南科技大学SRTP项目（2012214）
