摘要
目的分析老年患者单侧颈内动脉系统血管狭窄或闭塞后的磁共振灌注加权成像(perfusion weighted imaging,PWI)表现及影响灌注受损程度的相关性因素。方法通过数字减影血管造影筛选出单侧颈内动脉或大脑中动脉狭窄或闭塞,且对侧颈内动脉系统无严重狭窄的老年患者33例;采集入选患者的一般临床资料;利用PWI采集入选患者的灌注参数,根据灌注损伤的严重程度分为4期,作为PWI基线资料。对可能影响灌注损伤程度的相关因素进行统计学分析。结果对入选患者性别、年龄、临床症状、血管病变部位、代偿途径、脑血管狭窄(TICI)分级与PWI分级进行相关性分析显示,PWI分级与年龄(P=0.0040)和TICI分级(P=0.0047)有相关性;与病变部位(P=0.0568)可能存在相关性;与患者的性别、狭窄程度、代偿途径、临床症状无相关性。结论 PWI在评价单侧颈内动脉系统缺血引起灌注损伤方面具有明确作用。
Objective To analyze the magnetic resonance perfusion-weighted imaging （PWI） of unilateral internal carotid artery stenosis or occlusion in elderly patients and its related factors.Methods Clinical data about 33 elderly patients with internal carotid artery or middle cerebral artery stenosis/occlusion but without severe contralateral stenosis were collected by digital subtraction angiography.Their perfusion parameters were collected by PWI.Their perfusion damage was divided into 4 stages and used as the PWI baseline data.The influencing factors for perfusion damage were analyzed.Results The correlation of age,gender,clinical manifestations,vascular lesion site,compensation degree and TICI with PWI was analyzed.Age （P=0.0040） and TICI （P=0.0047） were related with the PWI.PWI injury maybe related to occlusion segment （P=0.0568）,but not related to sex,degree of stenosis,compensatory pathways,and clinical symptoms.Conclusion PWI plays an important role in assessment of unilateral carotid artery ischemia-induced perfusion damage.
出处
《中华老年心脑血管病杂志》
CAS
2015年第1期10-13,共4页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
关键词
颈动脉狭窄
梗死
大脑中动脉
磁共振成像
血管造影术
数字减影
carotid stenosis
infarction, middle cerebral artery
magnetic resonance imaging
angiography, digital subtraction
