摘要
目的 明确6 min步行试验(6MWT)距离用于诊断糖尿病外周动脉疾病(PAD)的价值,探讨6MWT作为PAD初筛指标的可行性.方法 选择2012年1~12月上海市第一人民医院分院门诊及住院的2型糖尿病患者160例作为研究对象,患者分别进行踝臂指数(ABI)检测以及6MWT,探讨两者的相关性.结果 不同ABI值的2型糖尿病患者的6MWT比较,差异有统计学意义(t=11.99,P<0.05),且6MWT与ABI呈正相关(r=0.827,P <0.01);受试者工作特征曲线分析显示6MWT对PAD(以ABI<0.9为标准)有鉴别价值(药时曲线下面积为0.936,P<0.01),当将6MW距离<408 m 时,其诊断PAD的灵敏度和特异度分别为90.8%和88.4%.结论 6MWT检测简单、方便、安全、康价,适合相对“健康”的糖尿病患者进行早期的PAD筛查.
Objective To identify the value of 6-minute walking test (6MWT) in diagnosing peripheral arterial disease (PAD) of diabetic patients and explore the feasibility of using 6MWT to prescreen PAD.Methods A total of 160 patients with type 2 diabetes admitted in Shanghai First People's Hospital from Jan.to Dec.2012 were selected as objects.The patients received both 6-MWT and ankle brachial index (ABI) measurement,and the correlation between the two results were analyzed.Results The 6MWT values of diabetic patients with different ABI values had statistically significant differences (t =11.99,P 〈 0.05),6MWT value and ABI value showed positive correlation in diagnosing PAD(r =0.827,P 〈0.001).Receiver operating characteristic(ROC) curves confirmed that 6MWT could significantly differentiate PAD(AUC =0.936,P 〈0.01).When 6MWT 〈 408 m,its sensitivity of diagnosing PAD was 90.8%,and the specificity was 88.4%.Conclusion 6MWT is simple,convenient,safe and cheap,it's feasible for early screening of PAD in mild diabetic patients.
出处
《医学综述》
2015年第1期151-153,共3页
Medical Recapitulate
关键词
外周血管病
6
MIN步行试验
踝臂指数
Peripheral arterial disease
6 minutes walking test
Ankle brachial index