摘要
目的观察降压、调脂联合治疗老年性高血压病合并高脂血症的临床疗效。方法将100例高血压病合并高脂血症的老年患者随机分为对照组和治疗组,各50例,对照组口服氢氯噻嗪和卡托普利治疗,治疗组在对照组治疗的基础上加用阿托伐他汀钙片,观察2组患者用药前后血压和血脂的变化,并比较2组患者6月内心脑血管事件的发生率。结果 2组患者治疗后血压均明显下降,与治疗前比较,差异有统计意义(P<0.05);治疗组治疗后血脂水平较治疗前显著改善(P<0.05),而对照组治疗后血脂水平与治疗前比较,差异无统计意义(P>0.05);治疗组6月内心脑血管病发生率(6.0%)显著低于对照组(16.0%)(P<0.05);治疗组血脂4项变化明显,与对照组比较差异有统计意义(P<0.05)。结论降压、调脂联合治疗老年性高血压病合并高脂血症效果明显,值得临床推广应用。
Objective To observe the healing efficacy of antihypertensive and lipid-modulating treatment for elderly hypertention complicated with hyperlipaemia. Methods 100 cases were radomly divided into control group（50 cases） and treatment group（ 50 cases）. The control group was intervened by hydrochlorothiazide and captopril. Besides that,the treatment group was treated with extra atorvastatin calcium. The changes of blood pressure and lipid were observed. The incidence of cardiovascular and cerebrovascular diseases in 6 months were compared. R esults After treatment,the blood pressure of two groups declined visibly,there was a significant difference（ P〈0.05）. The level of blood lipid in treatment group was improved greatly（ P〈0.05）,but there was no difference in control group（ P〈0. 05）. The incidence of cardiovascular and cerebrovascular diseases in treatment group（6.0%） was obviously lower than of control group（16.0%）（ P〈0.05）. Compared with control group,4 changes of blood lipid were evident in treatment group,there was a difference（ P〈0. 05）. Conclusion The treatment has a striking efficacy and it＇s well worthy of clinical popularization and application.
出处
《甘肃中医学院学报》
2014年第4期38-40,共3页
Journal of Gansu College of Traditional Chinese Medicine
关键词
降压
调脂
高血压病
高脂血症
疗效观察
antihypertension
lipid modulating
hypertention
hyperlipaemia
observation of healing efficacy
