期刊文献+

慢性阻塞性肺疾病血栓前状态研究进展 被引量:6

Research progress of chronic obstructive pulmonary disease
下载PDF
导出
摘要 慢性阻塞性肺疾病(COPD)是我国常见病、多发病,发病率越来越高,其急性加重多由感染引起,核心是气道炎症。在炎症反复刺激过程中,不断的启动凝血纤溶系统,凝血功能改变,致血液高凝状态,即血栓前状态(PTS)。这种血栓前状态极易并发深静脉血栓、肺栓塞及心血管事件等。因此,COPD患者早期及时进行抗凝治疗越来越受到临床医生的重视,而低分子量肝素治疗是临床较为成熟安全有效的抗凝治疗措施。 Chronic obstructive pulmonary disease( COPD) is a common disease and frequently-occurring disease in our country, Its incidence trends to raise year by year,acute exacerbations of Chronic obstructive pulmonary diseases(AECOPD) is usually caused by infection and pulmonary in flammation is the core.Inflammation of the stimulated repeatedly,start the blood coagulation systerm and fibrinolytic system,blood coagulation function is changed,lead to high blood coagulation state,also is Prethrombotic state(PTS). This state easily complicated by deep vein thrombosis、Pulmonary embolism、Cardiovascular events and so on.Therefore,early antico-agulant therapy more and more get the attention of the clinicians.And low-molecular-weight heparin anticoagulation therapy is safe and effective clinical anticoagulant therapy.
出处 《中国老年保健医学》 2014年第6期92-94,共3页 Chinese Journal of Geriatric Care
关键词 慢性阻塞性肺疾病 血栓前状态 肺血栓栓塞症 低分子量肝素 Chronic obstructive pulmonary disease COPD Prethrombotic state PTS Pulmonary thrombo emlism PTE low-molecular-weight heparin
  • 相关文献

参考文献25

  • 1慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华结核和呼吸杂志,2007,30(1):8-17. 被引量:8233
  • 2MacNee W. Acute exacerbations of COPD[ J]. Swiss Med Wkly,2003, 133 ( 17 - 18 ) :247 - 257. 被引量:1
  • 3Torbicki A, Perrier A, Konstantinides S, et al. Guidelines on the diagno- sis and management of acute pulmonary embolism : the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology ( ESC ) [ J ]. Eur Heart J, 2008,29 (18) :2276 -2315. 被引量:1
  • 4Sriano JB, Visiek GT, Muellerova H, et al. Patterns of comorbidities in newly diagnosed COPD and ashma in primary care [ J ]. Chest, 2005, 128(4) :2099 -2107. 被引量:1
  • 5詹娟,孙圣华.COPD患者缺氧对TNF-α系统的激活及与营养不良的相关性[J].医学临床研究,2003,20(12):881-884. 被引量:14
  • 6Tillie-Leblond I, Marquette CH, Perez T, et al. Pulmonary embolism in patients with unexplained exacerbation of chronic obstructive pulmonarydisease: prevalence and risk factors [ J]. Ann Intern reed, 2006, 144 (6) :390 -396. 被引量:1
  • 7王辰,杜敏捷,曹大德,翁心植,吴小青,常青,王瑜.慢性肺原性心脏病急性发作期肺细小动脉血栓形成的病理观察[J].中华医学杂志,1997,77(2):123-125. 被引量:498
  • 8lq.izkallab J, Man S, Sin DD. Prevalence of pulmonary embolism in acute exacerbations of COPD : a systematic review and meta-analysis [ J ]. Chest,2009,135(3) :786 -793. 被引量:1
  • 9Baueer KA, Rosenberg RD. The pathophysiology of the prethromboric state in humans:lnsightg gained from studies using nlsrkers of hemostat- ic system activation[ J]. Blood, 1987,70(2) :343. 被引量:1
  • 10Ashitani J, Mukae H, Arimura Y, et al. Elevated plasma procoagnlaunt and fibrinolytie markers in patients with chronic obstructive pulmonary disease[ J]. Intern Meal,2002,41:181 - 185. 被引量:1

二级参考文献82

共引文献8760

同被引文献107

引证文献6

二级引证文献33

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部