摘要
Toll样受体（TLR）是最特征性的病原模式识别受体,在宫颈人乳头瘤病毒（HPV）感染的过程中,TLR信号通路影响了HPV感染的转归,在宫颈高危HPV感染至宫颈癌变的进程中起到促进或抑制肿瘤的免疫调节作用.TLR的基因多态性与宫颈癌的发生也密切相关.
Toll like receptors （TLRs） are the most characteristic of pathogen recognition receptors.TLR signal pathway affects the outcome of cervical HPV infection,and plays double roles of promoting or inhibiting tumor in immune regulation for the process from high-risk HPV infection to cervical cancer.The polymorphism of TLR gene is closely related to the occurrence of cervical cancer.
出处
《国际肿瘤学杂志》
CAS
2014年第11期840-843,共4页
Journal of International Oncology
基金
浙江省自然科学基金（LY13H160026）
