摘要
目的：探讨二维超声联合四维超声对不同孕周产前超声筛查胎儿畸形的临床价值.方法：选择本院2010年1月～2012年11月就诊的不同孕周孕妇进行阶段性超声筛查,分为孕早期（11～17＋6周）、孕中期（18～27＋6周）、孕晚期（28～40＋6周）.对所有不同孕周的孕妇首先接受二维超声诊断检查,对初步怀疑胎儿畸形的孕妇再次实施二维超声联合四维超声检查,将不同孕周的二维超声检查结果以及联合四维超声检查与临床分娩结果分析比较.结果：2891例孕妇共分娩出2930例胎儿,经临床观察和随访发现124处畸形,其中泌尿生殖系统35处,消化系统31处,心脏23处,胸腹腔积液14处,胎儿肿瘤8处,皮肤水肿8处,四肢骨折5处.孕中期胎儿畸形检出率较高,且以泌尿生殖系统和消化系统为主,二维超声联合四维超声对不同孕期的胎儿畸形的临床诊断准确率显著高于单纯二维超声诊断准确率（P＜0.05）.结论：孕早期超声可对部分严重的胎儿畸形进行早期诊断,孕中期超声可筛查出部分胎儿结构异常,孕晚期超声则可提高迟发型胎儿畸形诊断检出率.超声检查时产前胎儿畸形检查的重要手段,二维超声联合四维超声检查可以显著提高胎儿畸形诊断率,是及时发现胎儿异常、降低出生缺陷的首选方法,应根据不同孕周的超声特点,提高检出率,为临床诊断提供可靠的参考.
Objective：To investigate the clinical value of the two-dimensional ultrasound combined with four-dimensional ultrasound in the diagnosis of fetal malformation in different gestational weeks.Methods：The pregnant women with different pregnant weeks from January 2010 to November 2012 were enrolled to subject to two-dimensional ultrasound screening during early pregnancy,the second trimester and late pregnancy.Women initially suspected to have fetal malformation were underwent two-dimensional ultrasound and four-dimensional ultrasonography.The two-dimensional ultrasound examination results and the two-dimensional ultrasound examination combined with four-dimensional ultrasound results and clinical delivery results were compared and analyzed.Results：A total of 2930 fetus were labored from 2891 pregnant women,124 congenital anomalies were detected through the clinical observation and follow-up,of which 35 genito urinary system,31 digestive system,23 heart,14 pleural effusion,8 fetal tumor,8 skin edema,5 limbs fracture malformation.The accuracy rate of two-dimensional ultrasound combined with four-dimensional ultrasound in the diagnosis of fetal malformation was significantly higher than that of simple two-dimensional ultrasound examination （P〈0.05）.Conclusion：The ultrasound for diagnosis is available for the severe fetal deformity in early pregnancy,and partly screening for fetal structural abnormalities during the second trimester,and it can increase the detection rate of late onset fetal malformation in the third trimester of pregnancy.The ultrasound examination is an important method for examination of fetal deformity,and combination of two-dimensional and four-dimensional ultrasonography can significantly improve the diagnostic rate of fetal malformation and is recognized as a preferred method for timely diagnosing the fetal abnormalities and reducing the birth defects.It is recommended that the diagnosis of fetal deformity should be based on the ultrasonic characteristics of different gestational wee
出处
《中国计划生育学杂志》
2015年第1期38-40,45,共4页
Chinese Journal of Family Planning
关键词
超声检查
产前胎儿畸形
二维超声
四维超声
Ultrasonography
fetal malformation
Two-dimensional ultrasound
Four-dimensional ultrasound
