摘要
目的 :介绍药物经济学评价中不确定性的概念及处理方法。方法 :通过查阅相关文献对药物经济学评价中的不确定性及其处理方法进行归纳和总结。结果 :不确定性的存在会影响药物经济学评价结果的精确度和可信度。不确定性可能产生在药物经济学评价过程中的各个阶段,而通过完善评价设计、改善统计和敏感度分析可有效评估并处理不确定性。结论 :为保证药物经济学评价的精确度和可信度,须从各个环节减少不确定性。同时,在评价过程中进行敏感度分析可以评估不确定性,有助于评价者控制不确定因素。
Objective： To introduce the concepts and treatment methods of uncertainty in pharmacoeconomic evaluation.Methods： The concepts and treatment methods of uncertainty in pharmacoeconomic evaluation were analyzed and summarized by searching relevant literatures.Results： The presence of uncertainty, which may be produced in the various stages of pharmacoeconomic evaluation process, can affect the accuracy and conifdence of the results of pharmacoeconomic evaluation and it can be effectively evaluated and treated by completing the research design and improving the statistical and sensitivity analysis.Conclusion： The uncertainty should be reduced from all aspects in order to ensure the accuracy and confidence in pharmacoeconomic evaluation. Meanwhile, the uncertainty can be assessed by sensitivity analysis during evaluation, which can assist the researcher to control the uncertainty factors.
出处
《上海医药》
CAS
2015年第1期10-13,共4页
Shanghai Medical & Pharmaceutical Journal
关键词
药物经济学
不确定性
敏感度分析
pharmacoeconomics
uncertainty
sensitivity analysis
