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Derlin-1与肺部疾病的关系 被引量:1

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摘要 Derlin-1是广泛存在于真核细胞内质网中的一种跨膜蛋白,是内质网相关降解途径(endoplasmic reticulum associated degradation,ERAD)中的一员[1]。在真核生物中,ERAD主要承载着细胞蛋白质量监控的作用,表现为对错误折叠蛋白的识别,将其逆向转运至胞浆,泛素化后降解,清除无功能蛋白在内质网内的堆积,缓解内质网应激[2]。
出处 《临床肺科杂志》 2015年第2期326-329,共4页 Journal of Clinical Pulmonary Medicine
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参考文献20

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二级参考文献10

  • 1王慧,程德云,关键,陈小菊,张永.单核细胞趋化蛋白-1与COPD大鼠气道炎症的研究[J].四川大学学报(医学版),2004,35(5):634-637. 被引量:9
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