期刊文献+

血清β-hCG对异位妊娠保守治疗的预测及在腹腔镜与传统开腹术后的表达差异 被引量:21

Prediction of serum β- hCG for conservative therapy of ectopic pregnancy and the difference of its expression between laparoscopy and traditional laparotomy
原文传递
导出
摘要 目的:研究血清β-HCG和孕酮对异位妊娠不同保守治疗方法中的预测价值。方法:选择2010年1月~2013年1月在临海市第二人民医院妇产科收治入院符合保守治疗条件的异位妊娠患者作为研究对象。根据治疗方案分为甲、乙两组,并回顾性选取异位妊娠行手术治疗的患者,分为腹腔镜手术和开腹术两组。结果:入组患者150例,甲组和乙组各75例。两组患者的年龄、BMI、孕次、产次、入组时β-h CG、孕酮水平、停经天数、包块大小和两组患者的保守治疗成功率等均无统计学差异(P〉0.05);随着血清β-h CG(χ^2=63.59,P〈0.001)和孕酮(χ^2=20.41,P〈0.001)水平的升高,保守治疗的成功率有明显下降的趋势;手术组中,腹腔镜术后1天、7天患者β-h CG水平下降速度均显著快于开腹手术患者(P〈0.01)。结论:β-h CG和孕酮水平是异位妊娠不同保守治疗方案效果的重要预测因素,且β-h CG下降速度是患者术后恢复速度的重要指标。 Objective: To research the values of serum human β -chorionic gonadotropin (β -hCG) and progesteronei in predic- tion of different conservative therapies of ectopie pregnancy. Methods: A total of 150 patients with ectopic pregnancy and meeting the crite- ria of conservative therapy were selected from department of gynecology and obstetrics in this hospital from January 2010 to January 2013 as study objects, then the patients were divided into group A (75 patients) and group B (75 patients) according to therapeutic schedule; the patients with ectopic pregnancy and treated with surgery were selected retrospectively, then they were divided into laparoseopy group and lap- arotomy group. Results: There was no statistically significant difference in age, body mass index (BMI), gravidity, parity, 13 -hCG and progesterone levels before treatment, the days of menopause, the size of mass and the successful rate of conservative therapy between the two groups (P 〉 0. 05 ) ; the successful rate of conservative therapy showed significant decreasing trend with the increases of serum 13 - hCG (X^2 = 63.59, P 〈 0. 001 ) and progesterone (X^2 = 20. 41, P 〈 0. 001 ) ; the decreasing speeds of serum β -hCG levels on the first day and the seventh day after laparoscopy were statistically significantly faster than those after laparotomy ( P 〈 0. 01 ) . Conclusion: β - hCG and progesterone levels are important predictive factors for effects of different conservative therapies of eetopie pregnancy, and the decreasing speed of serum β - hCG level is an important index of postoperative recovery.
作者 黄菊青
出处 《中国妇幼保健》 CAS 2015年第2期263-265,共3页 Maternal and Child Health Care of China
关键词 Β-HCG 异位妊娠 保守治疗 β - hCG Eetopie pregnancy Conservative therapy
  • 相关文献

参考文献11

  • 1Gong W,Li X,Ren H,et al.Superselective uterine arterial embolization combined with transcatheter intra-arterial methotrexate infusion in 40 cases with fallopian tube ectopic pregnancy[J].Clin Exp Obstet Gynecol,2013,40(2):222-226. 被引量:1
  • 2Bloch AJ,Bloch SA,Lyon M.Correlation ofβ-human chorionic gonadotropin with ultrasound diagnosis of ectopic pregnancy in the ED[J].Am J Emerg Med,2013,31(5):876-877. 被引量:1
  • 3Gebeh AK,Willets JM,Bari M,et al.Elevated anandamide and related N-acylethanolamine levels occur in the peripheral blood of women with ectopic pregnancy and are mirrored by changes in peripheral fatty acid amide hydrolase activity[J].J Clin Endocrinol Metab,2013,98(3):1226-1234. 被引量:1
  • 4Duenas-Garcia OF,Young C,Mikhail M,et al.Compliance with follow-up in an inner-city population treated with intramuscular methotrexate for suspected ectopic pregnancy[J].Int J Gynaecol Obstet,2013,120(3):254-256. 被引量:1
  • 5Little SH,Rockwell PG.Ectopic pregnancy:zero in on these lab and imaging clues[J].J Fam Pract,2012,61(11):678-686. 被引量:1
  • 6Shrestha J,Saha R.Comparison of laparoscopy and laparotomy in the surgical management of ectopic pregnancy[J].J Coll Physicians Surg Pak,2012,22(12):760-764. 被引量:1
  • 7Attia S,Ben-Nun A,Rabin T,et al.Ectopic pregnancy as a presenting symptom for lung cancer[J].Harefuah,2012,151(7):398-401,436. 被引量:1
  • 8Dillon KE,Sioulas VD,Sammel MD,et al.How and when human chorionic gonadotropin curves in women with an ectopic pregnancy mimic other outcomes:differences by race and ethnicity[J].Fertil Steril,2012,98(4):911-916. 被引量:1
  • 9Richardson A.Medical management of ectopic pregnancy:a10 -year case series[J].Hum Fertil(Camb),2012,15(3):116-120. 被引量:1
  • 10Crochet P,Agostini A.Prognostic value of human chorionic gonadotropin levels 4 days after a single dose of methotrexate for ectopic pregnancy[J].BJOG,2012,119(4):506-507. 被引量:1

同被引文献149

  • 1石永云,石杨杨,吴大保.腹腔镜下妊娠物清除及瘢痕修补术治疗Ⅲ型剖宫产瘢痕妊娠的临床分析[J].中国妇产科临床杂志,2020,21(2):188-189. 被引量:15
  • 2Refaat B, Dalton E, Ledger WL. Ectopic pregnancy secondary to in vitro fertilisation-embryo transfer: pathogenic mechanisms and management strategies [J]. Reprod Biol Endocrinol, 2015, 13 (1): 112-118. 被引量:1
  • 3Helmy S, Koch M, Kolbl H, et al. Correlation of the volume of ectopic pregnancy and MTX therapy outcome: a retrospec- tive cohort study [J].Eur J Obstet Gynecol Reprod Biol, 2015, 184 (12): 108-111. 被引量:1
  • 4Hadinata IE, Doyle LW, Thompson D, et al. Serum beta- hCG levels post-treatment of ectopic pregnancy with a single dose of intramuscular methotrexate [J]. Aust N Z J Obstet Gynaecol, 2015, 55 (2): 181-184. 被引量:1
  • 5Sahin S, Ozay A, Ergin E, et al. The risk of ectopic preg- nancy following GnRH agonist triggering compared with hCG triggering in GnRH antagonist IVF cycles [ J]. Arch Gynecol Obstet, 2015, 291 (1): 185-191. 被引量:1
  • 6Pollheimer J,Knfler M.The role of the invasive,placental trophoblast in human pregnancy[J].Wien Med Wochenschr,2012,162(9-10):187-190. 被引量:1
  • 7Basha S,Vaidhyanathan S,Pauletti GM.Selection of peptide ligands for human placental transcytosis systems using in vitro phage display[J].Methods Mol Biol,2011,716:141-156. 被引量:1
  • 8Xiang DJ,Chen LM,Gu JS,et al.Trichosanthin,a Chinese medicine for the medical treatment of ectopic pregnancy with high levels ofβ-h CG[J].Reprod Sci,2012,19(5):534-538. 被引量:1
  • 9司丽芬.探讨氨甲喋呤联合米非司酮治疗植入性胎盘的临床疗效[J].医学信息,2015,28(6):183. 被引量:1
  • 10Cabar FR,Fettback PB,Pereira PP,et al.Serum markers in the diagnosis of tubal pregnancy[J].Clinics(Sao Paulo),2008,63(5):701-708. 被引量:1

引证文献21

二级引证文献90

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部